A mineralocorticoid used to treat adrenal insufficiency

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Endocrine Pharmacology Quizlet Questions

Question 1 of 5

A mineralocorticoid used to treat adrenal insufficiency

Correct Answer: A

Rationale: The correct answer is A: Fludrocortisone. Fludrocortisone is a synthetic mineralocorticoid used to treat adrenal insufficiency by replacing aldosterone. It helps regulate electrolyte balance and blood pressure. Edrophonium, Azathioprine, and Neostigmine are not mineralocorticoids and are used for different conditions like myasthenia gravis and autoimmune diseases.

Question 2 of 5

Which of the following drugs would be appropriate for the treatment of acute iridocyclitis in a patient with eye pain and vision issues?

Correct Answer: D

Rationale: The correct answer is D: Dexamethasone. 1. Acute iridocyclitis is an inflammation of the iris and ciliary body, requiring a potent anti-inflammatory drug like a corticosteroid. 2. Dexamethasone is a potent corticosteroid that helps reduce inflammation in the eye, making it suitable for treating acute iridocyclitis. 3. Indomethacin (A) is a nonsteroidal anti-inflammatory drug (NSAID) which may not be as effective in controlling the inflammation in the eye. 4. Apraclonidine (B) and Timolol (C) are both used to lower intraocular pressure in conditions like glaucoma, not for treating inflammation like in acute iridocyclitis. In summary, Dexamethasone is the appropriate choice for treating acute iridocyclitis due to its potent anti-inflammatory properties, while the other options are not as effective for this specific condition

Question 3 of 5

Which of the following drugs would be most appropriate for postcoital contraception in this patient?

Correct Answer: C

Rationale: The correct answer is C: Levonorgestrel. Levonorgestrel is a progestin commonly used for emergency contraception due to its effectiveness in preventing pregnancy when taken shortly after unprotected intercourse. It works by inhibiting ovulation and fertilization. Clomiphene (A) is used to induce ovulation, not for emergency contraception. Leuprolide (B) is a gonadotropin-releasing hormone agonist used for conditions like endometriosis or prostate cancer, not for emergency contraception. Fulvestrant (D) is a selective estrogen receptor degrader used in breast cancer treatment, not for emergency contraception.

Question 4 of 5

Which of the following effects most likely occurred after a few days of therapy with a testosterone patch for adult-onset hypogonadism?

Correct Answer: A

Rationale: The correct answer is A because testosterone therapy for adult-onset hypogonadism typically suppresses the hypothalamic-pituitary-gonadal axis, leading to reduced LH secretion. This is due to negative feedback inhibition by the exogenous testosterone. Enhanced LH secretion is not expected. Choices B, C, and D are incorrect as testosterone therapy does not directly impact clotting factors synthesis, bone marrow stem cell growth, or erythropoietin synthesis.

Question 5 of 5

Which of the following actions most likely mediated the therapeutic efficacy of calcitriol in a patient with diffuse demineralization of bone?

Correct Answer: D

Rationale: The correct answer is D because calcitriol, the active form of vitamin D, increases intestinal calcium absorption by enhancing the expression of calcium-binding proteins and transporters. This helps in the treatment of diffuse demineralization of bone by ensuring an adequate supply of calcium for bone mineralization. Stimulation of liver hydroxylation of cholecalciferol (choice A) and renal α hydroxylase (choice B) are not directly related to the therapeutic efficacy of calcitriol. Decreased intestinal phosphate absorption (choice C) would not address the demineralization of bone because phosphate is not the primary mineral component of bone.

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