A married couple applied to the genetic consultation in order to consult about their child with multiple abnormalities (microcephaly, idiocy etc). The woman has had an illnesses during her pregnancy but she didn't take any teratogens or mutagens. The parents' and the child's karyotype is normal. Anamnesis study revealed that the family kept a cat. What gravidic disease caused the child's abnormalities?

Correct Answer: A

Rationale: The correct answer is A: Toxoplasmosis. Toxoplasmosis is a parasitic infection caused by Toxoplasma gondii, which can be transmitted to humans through contact with infected cat feces. During pregnancy, Toxoplasma infection can result in severe birth defects such as microcephaly and mental retardation in the child. In this case, the presence of a cat in the family and the child's abnormalities suggest a possible link to Toxoplasmosis. Other choices are incorrect because: B: Leishmaniasis is a parasitic disease transmitted by sandflies and does not typically cause the specific birth defects mentioned in the scenario. C: Dysentery is a bacterial infection that primarily affects the intestines and does not cause the neurological abnormalities described. D: Balantidiasis is a parasitic infection caused by Balantidium coli, a ciliated protozoan, but it is not associated with

Correct Answer: A

Rationale: Rationale: 1. Epstein-Barr virus causes infectious mononucleosis due to primary infection. 2. Certain types of cancer, such as Burkitt lymphoma and nasopharyngeal carcinoma, are associated with Epstein-Barr virus through oncogenic mechanisms. 3. Chickenpox and shingles are caused by varicella-zoster virus (HHV3). 4. Roseola infantum is caused by human herpesvirus 6 (HHV6). Summary: Choice A is correct as Epstein-Barr virus is linked to infectious mononucleosis and specific cancers. Choices B, C, and D are incorrect as they are caused by different herpesviruses.

Correct Answer: D

Rationale: The correct answer is D: P.aeruginosa. This bacterium is commonly found in water and soil, making its presence in indoor air an indicator of poor sanitation. Step 1: P.aeruginosa is an opportunistic pathogen known to cause infections in hospitals. Step 2: Its presence in the air indicates potential contamination and poor air quality. Step 3: Regular monitoring of P.aeruginosa levels can help assess the effectiveness of sanitation measures. Summary: A, B, and C are not suitable indicators of air sanitation in an enclosed space as they are not typically associated with environmental contamination or poor air quality.

Correct Answer: C

Rationale: The correct answer is C: All microorganisms. Sterilization aims to eliminate all microorganisms, including pathogenic and non-pathogenic ones, to ensure complete absence of viable organisms. This is crucial in medical, laboratory, and food preparation settings to prevent contamination and spread of infections. Choices A and B are incorrect because sterilization does not differentiate between pathogenic and non-pathogenic microorganisms, aiming to eradicate all. Choice D is incorrect as sterilization does involve releasing subjects (microorganisms) using physical methods.

Correct Answer: A

Rationale: The correct answer is A, Clostridium botulinum. This bacterium produces botulinum toxin, leading to botulism. It is commonly found in soil and improperly canned food. Clostridium tetani causes tetanus, Staphylococcus aureus causes food poisoning, and Salmonella enterica causes salmonellosis. Therefore, A is correct due to its association with botulism, while the other choices are incorrect for causing different diseases.

Correct Answer: D

Rationale: The correct answer is D: Structure of cell wall. When studying a bacterial smear stained by the Ozheshko method, the focus is on the cell wall structure. This staining method highlights the cell wall morphology, allowing for detailed examination. Flagella, spores, and capsules are not typically visualized using this staining method. Flagella require special staining techniques, spores are usually observed through specific staining methods like Schaeffer-Fulton, and capsules are not easily visualized with the Ozheshko staining method. Therefore, the structure of the cell wall is the most relevant feature to study in this context.

Correct Answer: D

Rationale: The correct answer is D, Salmonella typhi, because it is a motile bacterium due to possessing flagella that aid in movement. Bacillus anthracis (A) is non-motile, Klebsiella pneumoniae (B) lacks flagella for motility, and Shigella flexneri (C) is non-motile as well. Salmonella typhi (D) is known for its flagella-driven motility, allowing it to move and spread within its host and environment. Flagella are essential for bacterial motility, enabling them to navigate and colonize different environments efficiently.

Correct Answer: C

Rationale: The correct answer is C: Negative stain. Negative staining uses acidic dyes which are repelled by the bacterial cell wall components, highlighting bacteria with a large amount of peptidoglycan. Acid-fast stain (A) is used to identify Mycobacterium species with waxy cell walls. Gram stain (B) differentiates bacteria into Gram-positive and Gram-negative based on cell wall composition. Option D is a duplicate of option C and is incorrect.

Correct Answer: C

Rationale: The correct answer is C: Leishmaniasis. The description of thin microorganisms with 12-14 uniform tendrils, 10-13 micrometers in length, and pale pink color matches the characteristics of Leishmania parasites seen in Giemsa-stained samples. Leishmania parasites are known to have a distinctive appearance with pointed tips and a specific size range. Syphilis (choice A) is caused by Treponema pallidum, which appears as tightly coiled spirochetes, not tendrils. Trypanosomiasis (choice B) is caused by Trypanosoma parasites, which have a different morphology and staining pattern. Relapsing fever (choice D) is caused by Borrelia recurrentis, which does not match the description given. Therefore, the correct choice is C as the description aligns closely with the characteristic features of Leishmania parasites.