A married couple applied to the genetic consultation in order to consult about their child with multiple abnormalities (microcephaly, idiocy etc). The woman has had an illnesses during her pregnancy but she didn't take any teratogens or mutagens. The parents' and the child's karyotype is normal. Anamnesis study revealed that the family kept a cat. What gravidic disease caused the child's abnormalities?

Correct Answer: A

Rationale: The correct answer is A: Toxoplasmosis. Toxoplasmosis is a parasitic infection caused by Toxoplasma gondii, which can be transmitted to humans through contact with infected cat feces. During pregnancy, Toxoplasma infection can result in severe birth defects such as microcephaly and mental retardation in the child. In this case, the presence of a cat in the family and the child's abnormalities suggest a possible link to Toxoplasmosis. Other choices are incorrect because: B: Leishmaniasis is a parasitic disease transmitted by sandflies and does not typically cause the specific birth defects mentioned in the scenario. C: Dysentery is a bacterial infection that primarily affects the intestines and does not cause the neurological abnormalities described. D: Balantidiasis is a parasitic infection caused by Balantidium coli, a ciliated protozoan, but it is not associated with

Correct Answer: D

Rationale: The correct answer is D because enveloped viruses have a lipid bilayer envelope derived from the host cell membrane, which is a complex structure, not exhibiting any specific symmetry. Choice A (cubic symmetry) is incorrect as enveloped viruses do not have any specific geometric shape. Choice B (spiral symmetry) is incorrect as this type of symmetry is typically seen in non-enveloped viruses like helical viruses. Choice C (complex symmetry) is also incorrect as enveloped viruses do not exhibit a specific symmetrical pattern. Therefore, the correct answer is D because enveloped viruses do not have a defined symmetry and can vary in shape and structure.

Correct Answer: D

Rationale: The correct answer is D: BSL4. Ebola viruses are highly infectious and pose a high risk to laboratory workers. BSL4 facilities are designed to handle agents that pose a severe threat to human health and have no available vaccines or treatments. These facilities have strict guidelines for handling infectious agents, including full-body suits, negative air pressure, and decontamination processes to prevent any possible exposure. BSL1, BSL2, and BSL3 are not adequate for handling Ebola viruses due to their lower levels of containment and safety measures.

Correct Answer: B

Rationale: The correct answer is B: genotype. The genotype refers to the actual genetic makeup of an organism, including all the genes and alleles present in its DNA. This determines the traits and characteristics of an organism. Phenotype (A) is the observable physical or biochemical characteristics of an organism. Conjugation (C) is a process in bacteria involving the transfer of genetic material. Construct (D) is not a term related to genetics. Therefore, the correct choice is B as it specifically refers to the genetic composition of an organism.

Correct Answer: A

Rationale: The correct answer is A: prions. Prions are misfolded proteins that can cause spongiform encephalopathy by inducing normal proteins to misfold as well. Prions lack genetic material, distinguishing them from viruses (B), bacteria (C), and fungi (D), which all contain genetic material and cannot directly cause spongiform encephalopathy through protein misfolding.

Correct Answer: B

Rationale: The correct answer is B: Staphylococcus aureus. This bacteria is known to cause skin infections and toxic shock syndrome due to its ability to produce toxins that can lead to severe symptoms. Staphylococcus aureus is commonly found on the skin and can enter the body through cuts or wounds, causing infections. Other choices are incorrect because Pseudomonas aeruginosa typically causes infections in immunocompromised individuals, Micrococcus luteus is a common skin bacterium that is not typically pathogenic, and Propionibacterium acnes is associated with acne, not skin infections or toxic shock syndrome.

Correct Answer: D

Rationale: The correct answer is D (All of the above) as all three bacteria (Escherichia coli, Salmonella enterica, Neisseria meningitidis) produce endotoxins causing fever and shock. Endotoxins are lipopolysaccharides found in the outer membrane of Gram-negative bacteria and can trigger an immune response leading to fever and shock. Escherichia coli and Salmonella enterica are common causes of food poisoning and sepsis, while Neisseria meningitidis is responsible for meningococcal meningitis and septicemia. Therefore, all three choices are correct in producing endotoxins that can cause fever and shock.

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This is because Entamoeba histolytica is known to cause amebic dysentery, leading to chronic diarrhea. The presence of cysts with four nuclei in the stool sample is characteristic of Entamoeba histolytica. Giardia lamblia (choice B) is known to cause diarrhea but does not present with cysts containing four nuclei. Balantidium coli (choice C) is a ciliated protozoan that can cause diarrhea, but it does not have cysts with four nuclei. Trichomonas hominis (choice D) is a non-pathogenic protozoan commonly found in the human colon and is not associated with causing chronic diarrhea or cysts with four nuclei.

Correct Answer: A

Rationale: The correct answer is A: Helicobacter pylori. This bacterium is a major cause of gastric ulcers by disrupting the balance between aggressive (acid, pepsin) and defensive (mucus, bicarbonate, prostaglandins) factors in the stomach lining. H. pylori infection leads to inflammation, weakening the protective mucosal barrier, making the stomach more susceptible to damage. Choices B, C, and D are defensive factors that help protect the stomach lining and prevent ulcer formation, so they do not contribute to the development of gastric ulcers.