A married couple applied to the genetic consultation in order to consult about their child with multiple abnormalities (microcephaly, idiocy etc). The woman has had an illnesses during her pregnancy but she didn't take any teratogens or mutagens. The parents' and the child's karyotype is normal. Anamnesis study revealed that the family kept a cat. What gravidic disease caused the child's abnormalities?

Correct Answer: A

Rationale: The correct answer is A: Toxoplasmosis. Toxoplasmosis is a parasitic infection caused by Toxoplasma gondii, which can be transmitted to humans through contact with infected cat feces. During pregnancy, Toxoplasma infection can result in severe birth defects such as microcephaly and mental retardation in the child. In this case, the presence of a cat in the family and the child's abnormalities suggest a possible link to Toxoplasmosis. Other choices are incorrect because: B: Leishmaniasis is a parasitic disease transmitted by sandflies and does not typically cause the specific birth defects mentioned in the scenario. C: Dysentery is a bacterial infection that primarily affects the intestines and does not cause the neurological abnormalities described. D: Balantidiasis is a parasitic infection caused by Balantidium coli, a ciliated protozoan, but it is not associated with

Correct Answer: C

Rationale: The correct answer is C: rotaviruses. Rotaviruses are the most common cause of infectious diarrhea in infants and children due to their highly contagious nature and ability to spread easily in childcare settings. They are known to cause severe diarrhea, vomiting, and dehydration in young children. Noroviruses (A), adenoviruses (B), and caliciviruses (D) can also cause diarrhea, but rotaviruses are specifically known for their prevalence and severity in the pediatric population. This is why C is the correct answer.

Correct Answer: B

Rationale: The correct answer is B: genotype. The genotype refers to the actual genetic makeup of an organism, including all the genes and alleles present in its DNA. This determines the traits and characteristics of an organism. Phenotype (A) is the observable physical or biochemical characteristics of an organism. Conjugation (C) is a process in bacteria involving the transfer of genetic material. Construct (D) is not a term related to genetics. Therefore, the correct choice is B as it specifically refers to the genetic composition of an organism.

Correct Answer: A

Rationale: The correct answer is A: Candida fungi. Candida fungi are known to cause oral thrush, characterized by whitish spots on the oral mucosa. The presence of gram-positive oval budding cells in the smear preparations is indicative of Candida species. Staphylococci (choice B) are gram-positive cocci, not oval budding cells. Sarcinae (choice C) are gram-positive bacteria that form cuboidal packets, not oval budding cells. Actinomycetes (choice D) are filamentous gram-positive bacteria, not oval budding cells like Candida fungi.

Correct Answer: A

Rationale: Step-by-step rationale for choice A: 1. Viruses contain genetic material in the form of nucleic acids (DNA or RNA). 2. Proteins are essential for the structure and function of viral particles. 3. Nucleic acids (genetic material) and proteins are the two main components of viruses. 4. Therefore, choice A (nucleic acid and proteins) is correct. Summary: - Choice B (nucleic acids and lipids) is incorrect as lipids are not a main structural component of viruses. - Choice C (lipids and proteins) is incorrect as nucleic acids are essential components of viruses. - Choice D (proteins and glycoproteins) is incorrect as glycoproteins are a type of protein and not a separate component in viruses.

Correct Answer: D

Rationale: The correct answer is D: Fifth disease. Rubella virus is associated with Fifth disease, also known as erythema infectiosum. It is caused by parvovirus B19, not rubella virus. Mumps (choice A) is caused by the mumps virus. Roseola (choice B) is caused by human herpesvirus 6 or 7. Rubeola (choice C) is the scientific name for measles, caused by the measles virus. Therefore, the correct answer is Fifth disease as it is the disease associated with rubella virus.

Correct Answer: B

Rationale: The correct answer is B: Escherichia coli. E. coli is a common bacterium found in the gastrointestinal tract and is a leading cause of UTIs. It has specific virulence factors that enable it to adhere to and infect the urinary tract. Salmonella enterica causes food poisoning, Vibrio cholerae causes cholera, and Streptococcus pyogenes causes strep throat and skin infections, not UTIs. Therefore, B is the correct answer as it is the only bacterium known for causing UTIs.

Correct Answer: A

Rationale: The correct answer is A because penicillins and cephalosporins inactivate transpeptidase activity of penicillin binding proteins, leading to disruption of bacterial cell wall synthesis. This mechanism makes them bactericidal, not bacteriostatic (choice B). Choice C is incorrect as penicillins and cephalosporins target cell wall synthesis, not the cytoplasmic membrane. Choice D is incorrect as option A is the correct statement.

Correct Answer: D

Rationale: The correct answer is D (All of the above) as all three bacteria (Escherichia coli, Salmonella enterica, Neisseria meningitidis) produce endotoxins causing fever and shock. Endotoxins are lipopolysaccharides found in the outer membrane of Gram-negative bacteria and can trigger an immune response leading to fever and shock. Escherichia coli and Salmonella enterica are common causes of food poisoning and sepsis, while Neisseria meningitidis is responsible for meningococcal meningitis and septicemia. Therefore, all three choices are correct in producing endotoxins that can cause fever and shock.