A man was admitted to the hospital on the 5th day of disease that manifested itself by jaundice, muscle aching, chill, nose bleedings. In course of laboratory diagnostics a bacteriologist performed darkfield microscopy of the patient's blood drop. Name a causative agent of this disease:

Correct Answer: A

Rationale: The correct answer is A: Leptospira interrogans. Darkfield microscopy is used to visualize spirochetes, which are spiral-shaped bacteria. Leptospira is a spirochete bacterium that causes leptospirosis, which presents with jaundice, muscle aching, chill, and nosebleeds. Leptospira is commonly transmitted through contact with contaminated water or soil. B: Borrelia dutlonii causes Lyme disease, which is transmitted by ticks and does not typically present with jaundice or nosebleeds. C: Calymmatobacterium granulomatis causes granuloma inguinale, a sexually transmitted infection that does not present with the symptoms described. D: Bartonella bacilloformis causes Carrion's disease, which presents with fever, anemia, and skin lesions but not jaundice or nosebleeds.

Correct Answer: A

Rationale: The correct answer is A: Trichomonas vaginalis. Trichomonas vaginalis is a flagellated protozoan that causes trichomoniasis, a sexually transmitted infection commonly found in vaginal discharges. In this case, the presence of flagellates in the vaginal discharge aligns with the characteristics of Trichomonas vaginalis. Leishmania donovani causes leishmaniasis, transmitted by sandflies. Trypanosoma gambiense causes African sleeping sickness through the tsetse fly bite. Trihomonas hominis is a non-pathogenic flagellate found in the human intestine. Therefore, the correct choice is A due to the correlation between the flagellates found in the vaginal discharge and the characteristics of Trichomonas vaginalis.

Correct Answer: A

Rationale: The correct answer is A: Toxoplasma. Toxoplasma gondii is a protozoan parasite that can infect the brain and cause vision loss. The description of half-moon-shaped organisms with a pointed end matches the appearance of Toxoplasma under the microscope. Toxoplasma is known to cause a condition called toxoplasmosis, which can lead to neurological symptoms such as vision loss. Leishmania, Lamblia, Amoeba, and Trichomonad are not known to cause brain infections or vision loss, making them incorrect choices.

Correct Answer: A

Rationale: The correct answer is A: Doxycycline. It is a broad-spectrum antibiotic effective against a wide range of bacteria, including those causing infections like Lyme disease and pneumonia. Doxycycline is often the first-line treatment for these infections due to its efficacy and low risk of resistance. Chloramphenicol (B) has serious side effects and is reserved for specific cases. Penicillin (C) is not effective against all bacteria and may not cover the specific infection. Streptomycin (D) is mainly used for certain types of bacterial infections and is not the optimal choice for the conditions mentioned in the question.

Correct Answer: C

Rationale: The correct answer is C: Escherichia coli. E. coli is the most common cause of acute cystitis. It typically presents with leukocytes and gram-negative bacilli in the urine. The green pigment production indicates pyocyanin, which is a characteristic of E. coli. Pseudomonas aeruginosa (A) can also produce green pigment, but it is less common in urinary tract infections. Proteus mirabilis (B) is associated with a swarming motility pattern on agar, not mucous colonies. Klebsiella pneumoniae (D) is associated with pneumonia and other respiratory infections, not cystitis.