A man is suffering from diarrhea. In summer he spent his vacation in the south at the sea coast. Bacteria with the following properties were detected in his feces: gram-negative curved mobile monotrichous bacilli that do not produce spores or capsules. They are undemanding to nutrient medium but require alkaline reaction (Ñ€H 8.5-9.5). Described are the agents of the following enteric infection:

Correct Answer: A

Rationale: Step-by-step rationale for why the correct answer is A (Cholera): 1. Gram-negative curved mobile monotrichous bacilli: Vibrio cholerae, the causative agent of cholera, fits this description. 2. Do not produce spores or capsules: Vibrio cholerae does not produce spores or capsules. 3. Require alkaline reaction (pH 8.5-9.5): Vibrio cholerae thrives in alkaline environments. 4. Enteric infection: Cholera is a classic example of an enteric infection transmitted through contaminated food or water. Summary of why other choices are incorrect: B: Shigellosis is caused by Shigella species, which are gram-negative, but they are not curved bacilli and do not require an alkaline pH. C: Typhoid fever is caused by Salmonella Typhi, which are gram-negative but are not curved bacilli and do not require an alkaline pH.

Correct Answer: A

Rationale: The correct answer is A: 1 chromosome. Bacterial cells typically have a singular circular chromosome that contains their genetic material. This chromosome is essential for the cell's survival and contains all the necessary genetic information for its functions. Choices B, C, and D are incorrect because they refer to the chromosome numbers found in human cells (23 pairs or 46 individual chromosomes). Bacteria, being prokaryotic organisms, have a simpler genetic makeup compared to eukaryotic organisms like humans, hence they possess only one chromosome.

Correct Answer: C

Rationale: The correct answer is C: Granuloma formation. In response to tuberculosis antigen (tuberculin), the immune system forms a granuloma at the injection site as a defense mechanism. Granulomas are organized collections of immune cells that wall off the antigen and prevent its spread. This process involves macrophages, T cells, and fibroblasts. Choice A (Cells cytotoxity) is incorrect because tuberculin test does not involve direct cell cytotoxicity. Choice B (Reagin type cytotoxity) is incorrect as reagin type hypersensitivity is associated with allergic reactions, not granuloma formation. Choice D (Immunocomplex cytotoxity) is also incorrect as immunocomplex cytotoxicity refers to tissue damage caused by immune complexes, not granuloma formation.

Correct Answer: B

Rationale: The correct answer is B: Zoonosis. Tularemia is primarily a zoonotic disease, meaning it is transmitted from animals to humans. The bacterium that causes tularemia, Francisella tularensis, commonly infects animals like rabbits, rodents, and ticks, which serve as reservoir hosts. Humans can get infected through direct contact with infected animals, insect bites, or contaminated water or soil. This zoonotic nature of tularemia distinguishes it from anthroponosis (A), which is transmitted only between humans, and sapronosis (C), which is transmitted through non-living environmental sources. Choice D is incorrect because there is a correct answer, which is zoonosis.

Correct Answer: A

Rationale: Rationale: Vibrio cholerae produces the exotoxin responsible for severe diarrhea. It causes cholera by disrupting the normal functioning of the intestines. Clostridium botulinum causes botulism, not diarrhea. Streptococcus pyogenes causes strep throat and skin infections. Salmonella enterica causes food poisoning, not severe diarrhea. Therefore, the correct answer is A.

Correct Answer: A

Rationale: The correct answer is A: Lowestein-Jensen. This is because Lowestein-Jensen medium is specifically designed to cultivate Mycobacterium tuberculosis, providing necessary nutrients and conditions for its growth. Loefller's medium is not optimal for cultivating M. tuberculosis. Choice C (All of the above) is incorrect as not all the options listed are suitable for cultivating M. tuberculosis. Choice D (None of the above) is also incorrect as Lowestein-Jensen is indeed the recommended growth medium for this bacterium.

Correct Answer: A

Rationale: The correct answer is A: Toxoplasma. Toxoplasma gondii is a protozoan parasite that can infect the brain and cause vision loss. The description of half-moon-shaped organisms with a pointed end matches the appearance of Toxoplasma under the microscope. Toxoplasma is known to cause a condition called toxoplasmosis, which can lead to neurological symptoms such as vision loss. Leishmania, Lamblia, Amoeba, and Trichomonad are not known to cause brain infections or vision loss, making them incorrect choices.

Correct Answer: C

Rationale: The correct answer is C because Gram staining after culture on Loeffler's medium or tellurite-containing medium will show the characteristic Chinese letter arrangement of Corynebacterium diphtheriae. This arrangement consists of metachromatic granules that stain more deeply than the rest of the cell. This specific staining pattern is a key diagnostic feature of C. diphtheriae in microbiological diagnosis of diphtheria. Choice A is incorrect because simply identifying the isolate as C. diphtheriae is not sufficient for diagnosis. Choice B is incorrect as C. diphtheriae can be stained via Gram staining despite its small cell size. Choice D is incorrect as option C is indeed correct for microbiological diagnosis of diphtheria.

Correct Answer: A

Rationale: The correct answer is A: Sandfly. Cutaneous leishmaniasis is transmitted by the bite of infected sandflies. These tiny insects are known vectors for Leishmania parasites. Sandflies are active during dusk and night, feeding on blood from mammals, including humans. Tick (B), mosquito (C), and tsetse fly (D) are not vectors for Leishmania parasites. Ticks transmit diseases like Lyme disease, mosquitoes transmit diseases like malaria, and tsetse flies transmit African trypanosomiasis. Therefore, the correct vector for cutaneous leishmaniasis is the sandfly due to its specific role in transmitting the Leishmania parasite.