ATI RN
Microbiology Chapter 14 Test Bank Questions
Question 1 of 9
A man died from an acute infectious disease accompanied by fever, jaundice, haemorrhagic rash on the skin and mucous membranes as well as by acute renal insufficiency. Histological examination of renal tissue (stained by Romanovsky-Giemsa method) revealed some convoluted bacteria looking like C and S letters. What bacteria were revealed?
Correct Answer: A
Rationale: The correct answer is A: Leptospira. The key features pointing to Leptospira are the presence of convoluted bacteria resembling C and S letters, which is characteristic of Leptospira species. Leptospirosis presents with fever, jaundice, haemorrhagic rash, and acute renal insufficiency. The other choices (B: Treponema, C: Spirilla, D: Borrelia) do not match the histological description or the clinical presentation of the case. Treponema is associated with syphilis, Spirilla with genus Spirochaeta, and Borrelia with Lyme disease, none of which match the given scenario.
Question 2 of 9
Which organism is responsible for cholera?
Correct Answer: B
Rationale: The correct answer is B: Vibrio cholerae. Cholera is caused by this specific bacterium. Vibrio cholerae produces a toxin that leads to severe diarrhea and dehydration. Salmonella typhi causes typhoid fever, Escherichia coli can cause various infections but not cholera, and Shigella dysenteriae causes dysentery, not cholera. Therefore, the correct choice is B.
Question 3 of 9
A patient with fever, headache, and neck stiffness had cerebrospinal fluid microscopy revealing Gram-negative diplococci. What is the likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Neisseria meningitidis. This bacterium is a Gram-negative diplococcus commonly associated with meningitis. Neisseria meningitidis is a leading cause of bacterial meningitis in young adults and adolescents. It is known for causing fever, headache, and neck stiffness. The other choices, Streptococcus pneumoniae, Haemophilus influenzae, and Klebsiella pneumoniae, are not typically Gram-negative diplococci and are not commonly associated with the symptoms described. Streptococcus pneumoniae is a Gram-positive coccus, Haemophilus influenzae is a Gram-negative coccobacillus, and Klebsiella pneumoniae is a Gram-negative rod. Therefore, Neisseria meningitidis is the most likely causative agent in this scenario.
Question 4 of 9
A bacteriological laboratory tests canned meat for botulinum toxin. Extract of the tested material and ABE botulinum antitoxin serum was introduced into the test group of mice; a control group of mice received the extract without antibotulinic serum. What serological reaction was used?
Correct Answer: A
Rationale: The correct answer is A: Neutralization. In this experiment, the ABE botulinum antitoxin serum is introduced along with the extract to neutralize the botulinum toxin. This is a specific type of serological reaction where the antitoxin serum binds to and neutralizes the toxin, preventing it from causing harm. Summary: - B: Precipitation involves the formation of visible insoluble complexes, which is not the case in this experiment. - C: Complement binding involves the activation of complement proteins, which is not the main mechanism at play here. - D: Double immunodiffusion is a technique to detect the presence of specific antigens or antibodies, but it is not directly related to the neutralization of toxins as seen in this experiment.
Question 5 of 9
Which of the following statements for S. Aureus is FALSE
Correct Answer: A
Rationale: The correct answer is A because Staphylococcus aureus can develop resistance to penicillin over time due to the production of beta-lactamase enzymes. This resistance mechanism makes it no longer susceptible to penicillin. The other choices are correct: B) S. aureus can produce beta hemolysis, C) it produces various toxins like hemolysins, leucocidins, and enterotoxins, and D) it shows a positive catalase reaction due to the presence of catalase enzyme that converts hydrogen peroxide to water and oxygen.
Question 6 of 9
A child suspected for tuberculosis underwent Mantoux test. 24 hours after allergen injection there appeared a swelling, hyperaemia and tenderness. What are the main components in the development of this reaction?
Correct Answer: A
Rationale: The correct answer is A: Mononuclears, T-lymphocytes and lymphokines. In a Mantoux test reaction, mononuclear cells, mainly T-lymphocytes, are activated by the injected allergen. These T-lymphocytes release lymphokines, leading to the observed swelling, hyperaemia, and tenderness. Granulocytes and IgG (choice B) are not the primary players in this type of delayed hypersensitivity reaction. Plasmatic cells (choice C) are not involved in the initial stages of this reaction. B-lymphocytes and IgM (choice D) are not the key components in the Mantoux test reaction.
Question 7 of 9
The compact structure in which the genome of the bacteria is located is called:
Correct Answer: A
Rationale: The correct answer is A: Nucleoid. The bacterial genome is located in the nucleoid, a region within the bacterial cell where the genetic material is condensed and organized. This structure is not the same as a nucleus found in eukaryotic cells. The other choices (B: Nucleotide and C: ATP) are incorrect because nucleotide refers to a building block of DNA or RNA, and ATP is a molecule used for energy transfer in cells, neither of which specifically houses the bacterial genome. Choice D: None of the above is incorrect as well, as the correct term for the compact structure containing the bacterial genome is the nucleoid.
Question 8 of 9
Aflatoxins are produced by:
Correct Answer: D
Rationale: The correct answer is D: Genus Aspergillus. Aflatoxins are toxic compounds produced by certain species of fungi, particularly Aspergillus species. Aspergillus flavus and Aspergillus parasiticus are well-known producers of aflatoxins. These fungi can contaminate crops such as peanuts, corn, and tree nuts, leading to potential health risks. Cryptococcus (A), Actinomyces (B), and Streptococcus (C) are not known to produce aflatoxins. It is important to be aware of the sources and implications of aflatoxin contamination to ensure food safety and public health.
Question 9 of 9
A 22-year-old patient is a clerk. His working day runs in a conditioned room. In summer he was taken by an acute disease with the following symptoms: fever, dyspnea, dry cough, pleural pain, myalgia, arthralgia. Objectively: moist rales on the right, pleural friction rub. X-ray picture showed infiltration of the inferior lobe. In blood: WBC - 11 · 109/l, stab neutrophils - 6%, segmented neutrophils - 70%, lymphocytes - 8%, ESR - 42 mm/h. What is the etiological factor pneumonia?
Correct Answer: C
Rationale: The correct answer is C: Streptococcus. Streptococcus pneumoniae is the most common etiological factor for community-acquired pneumonia in young adults. The symptoms described align with typical pneumococcal pneumonia presentation. Presence of pleural friction rub and infiltration in the X-ray support the diagnosis. The blood work showing elevated WBC count with a left shift (increased neutrophils and low lymphocytes) and elevated ESR is consistent with a bacterial infection. Legionella and Mycoplasma typically present with atypical pneumonia symptoms such as headache, confusion, and GI symptoms, which are not described in the case. Staphylococcus pneumonia is not a common cause of community-acquired pneumonia in young adults.