A lymph node punctate of a patient with suspected protozoa disease was examined. Examination of the stained specimen (Romanovsky's stain) revealed some crescent bodies with pointed end, blue cytoplasm and red nucleus. What protozoan were revealed in the smears?

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Microbiology Basic and Clinical Principles Test Bank Questions

Question 1 of 9

A lymph node punctate of a patient with suspected protozoa disease was examined. Examination of the stained specimen (Romanovsky's stain) revealed some crescent bodies with pointed end, blue cytoplasm and red nucleus. What protozoan were revealed in the smears?

Correct Answer: B

Rationale: The correct answer is B: Malarial plasmodiums. The description of crescent bodies with a pointed end, blue cytoplasm, and red nucleus corresponds to the characteristics of Plasmodium species seen in Romanovsky's stain. Plasmodium species are known to cause malaria and have distinct features like the ones described. Incorrect choices: A: Toxoplasmas - Toxoplasma gondii typically appear as tachyzoites or bradyzoites under staining, not crescent bodies. C: Dermotropic leishmania - Leishmania species appear as amastigotes in tissue smears, not crescent bodies. D: Viscerotropic leishmania - Similar to choice C, Leishmania species do not typically present as crescent bodies in stained specimens.

Question 2 of 9

The most common bacterial species in hospital environment is:

Correct Answer: B

Rationale: The correct answer is B: Staphylococcus aureus. This bacterium is commonly found in hospital environments due to its ability to colonize human skin and mucous membranes. It is a leading cause of hospital-acquired infections. Borrelia burgdorferi is mainly associated with Lyme disease transmitted by ticks, not commonly found in hospitals. Bacillus cereus is a foodborne pathogen, not typically prevalent in hospital settings. Staphylococcus haemolyticus is a coagulase-negative staphylococcus species, less pathogenic and less common in hospitals compared to Staphylococcus aureus.

Question 3 of 9

Rheumatic fever is an inflammatory disease and rare complication of:

Correct Answer: A

Rationale: Rheumatic fever is caused by untreated strep throat. Step 1: Strep throat is caused by Streptococcus bacteria. Step 2: If strep throat is not treated with antibiotics, it may lead to rheumatic fever due to the body's immune response attacking its own tissues. Summary: Gangrene, brucellosis, and tularemia are not associated with rheumatic fever.

Question 4 of 9

Which of the following bacteria is responsible for causing the disease known as pneumonia?

Correct Answer: D

Rationale: Rationale: 1. Streptococcus pneumoniae is a common cause of bacterial pneumonia. 2. Mycobacterium tuberculosis can cause a type of pneumonia called tuberculosis. 3. Escherichia coli is not typically associated with pneumonia. 4. "All of the above" includes both Streptococcus pneumoniae and Mycobacterium tuberculosis, which are known to cause pneumonia. Therefore, D is the correct answer.

Question 5 of 9

A blood culture from a patient with sepsis revealed Gram-negative diplococci. The bacteria were oxidase-positive and fermentative. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Neisseria meningitidis. Step 1: Gram-negative diplococci - characteristic of Neisseria species. Step 2: Oxidase-positive - Neisseria species are oxidase-positive. Step 3: Fermentative - Neisseria meningitidis is a fermentative bacterium. Therefore, Neisseria meningitidis is the most likely causative agent. Summary: - B: Neisseria gonorrhoeae is also a Neisseria species but is not fermentative. - C: Moraxella catarrhalis is oxidase-positive but not fermentative. - D: Haemophilus influenzae is not a Neisseria species and is not typically fermentative.

Question 6 of 9

A patient with fever and sore throat had a throat culture revealing Gram-positive cocci in chains. The bacteria were catalase-negative and beta-hemolytic. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. 1. Gram-positive cocci in chains: characteristic of Streptococcus species. 2. Catalase-negative: Streptococcus species are catalase-negative. 3. Beta-hemolytic: S. pyogenes is beta-hemolytic on blood agar. Therefore, S. pyogenes fits all these criteria. B: Streptococcus pneumoniae is catalase-negative but alpha-hemolytic, not beta-hemolytic. C: Enterococcus faecalis is catalase-negative, but not typically beta-hemolytic or in chains. D: Staphylococcus aureus is catalase-positive and not in chains.

Question 7 of 9

A 12-year-old boy presents with nausea, frequent repeated vomiting that first occurred after eating canned vegetables. Objectively: the patient has dry mucous membranes, muscular hypotonia, anisocoria, mydriasis, dysphagia and dysarthria. What is the most likely diagnosis?

Correct Answer: A

Rationale: The most likely diagnosis is A: Botulism. The symptoms, such as nausea, vomiting after eating canned vegetables, dry mucous membranes, muscular hypotonia, anisocoria, mydriasis, dysphagia, and dysarthria, are classic signs of botulism poisoning. Botulism is caused by the neurotoxin produced by Clostridium botulinum bacteria found in improperly canned or preserved food. The neurotoxin affects the nervous system, leading to symptoms like those described. Shigellosis (B), Salmonellosis (C), and Cholera (D) typically present with different symptoms such as diarrhea, fever, and abdominal pain, which are not seen in this patient.

Question 8 of 9

A 45 year old male died from disseminated tuberculosis. On autopsy the symptoms of tuberculosis were confirmed by both microscopical and histological analyses. What kind of hypersensitivity reaction underlies the process of granuloma development?

Correct Answer: A

Rationale: The correct answer is A: Delayed hypersensitivity reaction. In granuloma development in tuberculosis, macrophages present antigen to T cells, leading to a delayed hypersensitivity reaction. This triggers the recruitment of more macrophages and formation of granulomas. Antibody-dependent cytotoxicity (B) and complement-dependent cytotoxicity (C) involve antibodies and complement proteins in immediate hypersensitivity reactions, which are not the primary mechanisms in tuberculosis. Anaphylactic reaction (D) is an acute systemic allergic reaction mediated by IgE antibodies, not relevant to granuloma formation in tuberculosis.

Question 9 of 9

The most commonly acquired laboratory infections are caused by

Correct Answer: A

Rationale: The correct answer is A: bacteria. Bacteria are the most common cause of laboratory-acquired infections due to their ability to survive and multiply in various environments. They can easily contaminate lab equipment and surfaces, leading to infections if proper precautions are not taken. Viruses (choice B) are less common in laboratory-acquired infections as they require specific conditions to survive outside a host. Protozoans (choice C) are larger and less likely to be transmitted in a laboratory setting. Prions (choice D) are misfolded proteins and are not considered living organisms, making them an unlikely source of laboratory infections.

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