ATI RN
Pediatric Genetics Questions
Question 1 of 5
A linkage map:
Correct Answer: A
Rationale: A linkage map uses recombination frequencies to determine the relative order of genes on a chromosome.
Question 2 of 5
Cancer cells:
Correct Answer: C
Rationale: Cancer cells proliferate uncontrollably and can become immortal (e.g., HeLa cells), evading normal cell death.
Question 3 of 5
The Philadelphia translocation involves:
Correct Answer: A
Rationale: The Philadelphia chromosome (t(9;22)) creates the BCR-ABL fusion gene in chronic myeloid leukemia.
Question 4 of 5
With a germ-line mutation:
Correct Answer: D
Rationale: A germline mutation is present in all cells of an individual, inherited from a gamete.
Question 5 of 5
Which type of study would compare the incidence of colon cancer among Japanese and Americans of Japanese descent?
Correct Answer: B
Rationale: A population study compares disease incidence across groups, like ethnic populations.