A large-scale reaction with parapertussis and pertussis diagnosticums was made in order to make serological diagnostics of the whooping cough. At the bottom of the test-tubes with diagnosticum of Bordetella parapertussis a granular sediment formed. What antibodies did this reaction reveal?

Correct Answer: B

Rationale: The correct answer is B: Precipitins. When a granular sediment forms at the bottom of the test-tubes, it indicates the formation of antigen-antibody complexes that are insoluble and precipitate out of the solution. Precipitins are antibodies that specifically react with antigens to form insoluble complexes. Agglutinins cause clumping of cells, opsonins enhance phagocytosis, and bacteriolysins lyse bacteria. These processes do not result in the formation of a granular sediment, making them incorrect choices in this context.

Correct Answer: D

Rationale: Step 1: Formic acid is produced during fermentation by Actinomyces. Step 2: Actinomyces are known to produce organic acids like formic acid through fermentation. Step 3: Other choices like Streptococcus, Klebsiella, and Clostridium are not typically associated with formic acid production. Step 4: Actinomyces is the most likely candidate based on its fermentation capabilities. Summary: Actinomyces is the correct answer because it is known to produce formic acid during fermentation, while the other choices lack this specific metabolic function.

Correct Answer: B

Rationale: The correct answer is B: Precipitins. When a granular sediment forms at the bottom of the test-tubes, it indicates the formation of antigen-antibody complexes that are insoluble and precipitate out of the solution. Precipitins are antibodies that specifically react with antigens to form insoluble complexes. Agglutinins cause clumping of cells, opsonins enhance phagocytosis, and bacteriolysins lyse bacteria. These processes do not result in the formation of a granular sediment, making them incorrect choices in this context.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. The description of Gram-positive cocci in pairs with pointed ends and capsules matches the morphology of S. pneumoniae. This bacterium is known to cause pneumonia, especially in individuals with underlying conditions like COPD. Staphylococcus aureus (B) typically appears in clusters, not pairs. Klebsiella pneumoniae (C) is a Gram-negative rod, not a cocci. Neisseria meningitidis (D) is a Gram-negative diplococcus, not a cocci. Hence, based on the morphology and clinical context, Streptococcus pneumoniae is the likely microorganism causing pneumonia in this patient.

Correct Answer: D

Rationale: The correct answer is D because all the choices can contribute to hospital-acquired infections. New patients in the incubation period can spread infections, medical staff can inadvertently transmit infections, and contaminated medical instruments can also be a source of infections. Therefore, it is important to consider all these factors to prevent and control the spread of infections in a hospital setting.

Correct Answer: B

Rationale: The correct answer is B: Clostridium botulinum. This bacterium belongs to the Clostridium genus, known for its ability to produce endospores. Endospores are dormant, resistant structures that help bacteria survive harsh conditions. Staphylococcus aureus (A), Escherichia coli (C), and Neisseria gonorrhoeae (D) do not produce endospores. Staphylococcus aureus is a gram-positive bacterium known for causing various infections, but it does not form endospores. Escherichia coli is a gram-negative bacterium commonly found in the intestines of humans and animals, but it does not produce endospores. Neisseria gonorrhoeae is a gram-negative bacterium that causes the sexually transmitted infection gonorrhea, but it also does not form endospores.

Correct Answer: C

Rationale: The correct answer is C because infectious (non-sterile) immunity is achieved through the persistence of the infectious agent in the body, allowing the immune system to continuously recognize and combat the pathogen. This type of immunity provides long-lasting protection against future infections by the same agent. Choice A (cross-reactivity of antibodies) is incorrect as it refers to the ability of antibodies to recognize similar antigens, not necessarily related to infectious immunity. Choice B (toxemia and formation of antitoxic antibodies) is incorrect as it specifically relates to toxins produced by pathogens and the corresponding antibody response, not the persistence of the infectious agent itself. Choice D (neutralization of infectious agent) is incorrect as it describes the process of antibodies binding to and inactivating pathogens, but it does not necessarily lead to long-term immunity through the persistence of the infectious agent.

Correct Answer: B

Rationale: The capsule of Bacillus anthracis is made of polypeptide. This is because the capsule is composed of a protein-based material that surrounds the bacterium, providing protection and aiding in its virulence. Polysaccharides, lipids, and the absence of capsules are not characteristic of Bacillus anthracis' capsule structure, making choices A, C, and D incorrect, respectively.

Correct Answer: A

Rationale: The correct answer is A: Delayed hypersensitivity reaction. In granuloma development in tuberculosis, macrophages present antigen to T cells, leading to a delayed hypersensitivity reaction. This triggers the recruitment of more macrophages and formation of granulomas. Antibody-dependent cytotoxicity (B) and complement-dependent cytotoxicity (C) involve antibodies and complement proteins in immediate hypersensitivity reactions, which are not the primary mechanisms in tuberculosis. Anaphylactic reaction (D) is an acute systemic allergic reaction mediated by IgE antibodies, not relevant to granuloma formation in tuberculosis.