A healthy man is in a region with high risk of catching malaria. What drug should be administered for individual chemoprophylaxis of malaria?

Correct Answer: A

Rationale: The correct answer is A: Chingamin (also known as Chloroquine). Chingamin is the drug of choice for chemoprophylaxis of malaria in regions with high risk. It is effective against Plasmodium falciparum, the most common malaria parasite. Chingamin is well-tolerated, affordable, and has a long track record of use. Sulfalen (Choice B) is not commonly used for malaria prophylaxis. Tetracycline (Choice C) is not recommended for malaria prophylaxis due to poor efficacy and resistance development. Metronidazole (Choice D) is not effective against malaria parasites.

Correct Answer: B

Rationale: The correct answer is B: Cannot induce infectious disease. Saprophytes are microorganisms that obtain nutrients from decaying organic matter and do not cause infectious diseases in humans. They play a vital role in the ecosystem by decomposing dead organisms. Choice A is incorrect because saprophytes do not cause typical infections. Choice C is incorrect because saprophytes do not cause chronic infections. Choice D is incorrect because saprophytes do not cause mixed infections involving multiple pathogens. Therefore, the correct answer is B as saprophytes do not induce infectious diseases.

Correct Answer: B

Rationale: Step-by-step rationale for why B (Gamma Interferon) is the correct answer: 1. Gamma Interferon is a type of immunomodulator that helps regulate the immune response. 2. It activates macrophages and enhances the immune system's ability to fight infections. 3. Rifampin is an antibiotic, not an immunomodulator. 4. Hexacima and Pentaxim are combination vaccines, not immunomodulators. In summary, Gamma Interferon is the correct answer as it directly influences the immune response, while the other choices are not immunomodulators.

Correct Answer: B

Rationale: The correct answer is B because endotoxins are part of the outer membrane of gram-negative bacteria. When these bacteria undergo cell lysis, the endotoxins are released, causing harmful effects. This process does not occur during bacterial replication (choice A), antibody production (choice C), or formation of spores (choice D). Bacterial replication involves the creation of new bacterial cells, not the release of endotoxins. Antibody production is the immune response to pathogens, not the direct cause of endotoxin release. Spores are dormant structures formed by some bacteria, which are not directly related to the release of endotoxins.

Correct Answer: B

Rationale: The correct answer is B because in immune reactions, a large lattice is formed when antigens and antibodies are in optimal proportion. This optimal ratio allows for the formation of a strong antigen-antibody complex, leading to the aggregation of immune complexes into large lattice structures. When antibodies are in excess (choice A), there may not be enough antigens to form a stable lattice. Similarly, when antigens are in excess (choice C), there may be insufficient antibodies to form a strong lattice. Choice D is incorrect because the optimal proportion of antigens and antibodies is crucial for the formation of large lattices in immune reactions.

Correct Answer: B

Rationale: The correct answer is B, Streptococcus pneumoniae. This bacterium is the classic causative agent of croupous pneumonia due to its ability to infect the lungs and cause inflammation. Streptococcus pneumoniae is a common pathogen known for causing pneumonia in both adults and children. It is characterized by the presence of a capsule that helps it evade the host immune system. Choice A, Chlamydia pneumoniae, is not the correct answer as it is more commonly associated with atypical pneumonia. Choice C, Mycoplasma pneumoniae, is also associated with atypical pneumonia and not croupous pneumonia. Choice D, Staphylococcus aureus, can cause pneumonia, but it is not the classic causative agent of croupous pneumonia.

Correct Answer: B

Rationale: The correct answer is B: IgM. IgM is the first antibody synthesized by the infant soon after birth. It is produced by B cells in response to initial exposure to antigens. IgA is mainly found in mucosal areas, IgG is transferred from mother to fetus, and IgD functions in the early stages of B cell development. Therefore, IgM is the most suitable choice as the antibody synthesized by the infant soon after birth.

Correct Answer: D

Rationale: The correct answer is D: Relenza and Tamiflu. Both Relenza and Tamiflu are anti-influenza drugs that target the neuraminidase enzyme of the influenza virus, thereby inhibiting its replication and spread. Maxi Grip (A) is not an anti-influenza drug, Theraflu (B) contains different active ingredients, and Amantadine and Rimantadine (C) target a different viral protein, M2 ion channel. Therefore, choices A, B, and C are incorrect as they do not specifically target neuraminidase for influenza treatment.

Correct Answer: A

Rationale: The correct answer is A: Two-layer. In gram-positive bacteria, the cell envelope consists of two layers: the thick peptidoglycan layer and the cytoplasmic membrane. The peptidoglycan layer is much thicker compared to gram-negative bacteria, providing structural support and protection. The cytoplasmic membrane is located beneath the peptidoglycan layer and serves as a barrier between the cytoplasm and the external environment. The other choices are incorrect because gram-positive bacteria do have a cell envelope, it is composed of two layers, not three layers, and it is not just a single layer. Choice D is incorrect as it states that there is no cell envelope in gram-positive bacteria, which is not true.