A healthcare professional is preparing to administer Filgrastim for the first time to a client who has just undergone a bone marrow transplant. Which of the following interventions is appropriate?

Correct Answer: D

Rationale: When administering Filgrastim, only one dose should be withdrawn from the vial, and the vial should then be discarded. This medication should not be shaken but gently inverted to mix it before withdrawing the appropriate dose. It is important to follow these guidelines to ensure the medication's efficacy and prevent contamination or errors in dosing. Refrigeration is not required for Filgrastim; it should be stored at room temperature until just before administration.

Correct Answer: C

Rationale: In this scenario, the correct answer is C) Bone marrow suppression. Methotrexate is a disease-modifying antirheumatic drug (DMARD) commonly used to treat Rheumatoid Arthritis. One of the most significant adverse effects of methotrexate is bone marrow suppression, which can lead to decreased production of blood cells (anemia, leukopenia, thrombocytopenia). Monitoring for signs of infection, anemia, and easy bruising is crucial when a patient is on methotrexate therapy. Option A) Insomnia is incorrect because methotrexate is not known to cause insomnia as an adverse effect. Option B) Hypertension is also incorrect because methotrexate does not typically cause hypertension. Option D) Constipation is not a common adverse effect of methotrexate either. Educationally, understanding the potential adverse effects of medications is essential for nurses to provide safe and effective care to their patients. Monitoring for specific adverse effects based on the medication prescribed can help prevent complications and improve patient outcomes. In the case of methotrexate, being vigilant for bone marrow suppression is critical in ensuring the patient's safety and well-being.

Correct Answer: C

Rationale: The correct instruction for a client starting clonidine therapy for hypertension is to avoid driving until their reaction to the medication is known. Clonidine can cause drowsiness, so it is important for the client to refrain from activities that require alertness until they are aware of how the medication affects them. This precaution ensures the client's safety and the safety of others while taking the medication.

Correct Answer: B

Rationale: The correct instruction for a client taking furosemide is to eat a diet high in potassium. Furosemide is a loop diuretic that can lead to potassium loss, potentially causing hypokalemia. Consuming foods rich in potassium can help maintain normal potassium levels in the body and counteract the potential side effect of furosemide.

Correct Answer: B

Rationale: Urinary retention is a common anticholinergic effect associated with amitriptyline, a tricyclic antidepressant. Amitriptyline can cause relaxation of the bladder sphincter muscles, leading to urinary retention. Monitoring for this adverse effect is crucial to prevent complications and ensure prompt intervention if needed.