ATI RN
microbiology an introduction test bank Questions
Question 1 of 9
A Gram-stained smear from a wound revealed Gram-positive rods with terminal spores. The bacteria were anaerobic and produced gas. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Clostridium perfringens. This bacterium is an anaerobic, Gram-positive rod that forms terminal spores and produces gas. It is commonly associated with wound infections and gas gangrene. Clostridium botulinum causes botulism and does not typically present with gas production. Bacillus anthracis is an aerobic, Gram-positive spore-forming bacterium causing anthrax. Clostridium tetani causes tetanus and does not produce gas. Thus, based on the characteristics described in the question, Clostridium perfringens is the most likely causative agent.
Question 2 of 9
Rheumatic fever is usually a complication of a(n) __________ infection.
Correct Answer: B
Rationale: Rationale: 1. Streptococcus pyogenes is the causative agent of strep throat. 2. If untreated, strep throat can lead to rheumatic fever. 3. Rheumatic fever is an autoimmune complication of streptococcal infections. 4. E. coli, S. epidermidis, and S. aureus are not typically associated with rheumatic fever.
Question 3 of 9
Which bacteria is responsible for causing the disease known as leprosy?
Correct Answer: A
Rationale: The correct answer is A: Mycobacterium leprae. This bacterium is responsible for causing leprosy. Mycobacterium leprae is a slow-growing bacterium that affects the skin and nerves, leading to the characteristic symptoms of leprosy. Neisseria gonorrhoeae is a sexually transmitted bacterium causing gonorrhea. Streptococcus pneumoniae causes pneumonia and other respiratory infections. Clostridium perfringens is associated with food poisoning and gas gangrene. Therefore, the correct answer is A because Mycobacterium leprae specifically causes leprosy, while the other choices are associated with different diseases.
Question 4 of 9
The primary target of beta-lactam antibiotics is:
Correct Answer: C
Rationale: The primary target of beta-lactam antibiotics is cell wall synthesis. These antibiotics inhibit enzymes called penicillin-binding proteins, which are essential for building the bacterial cell wall. By disrupting cell wall synthesis, beta-lactam antibiotics weaken the cell wall, leading to bacterial cell lysis and death. Protein synthesis (Choice A), DNA replication (Choice B), and folic acid synthesis (Choice D) are not directly targeted by beta-lactam antibiotics, making them incorrect choices.
Question 5 of 9
UN volunteers have arrived in Nigeria to assist the locals in aftermath of earthquakes. What drug should they prescribe for individual chemoprophylaxis of malaria?
Correct Answer: D
Rationale: The correct answer is D: Primaquine. Primaquine is used for individual chemoprophylaxis of malaria caused by Plasmodium vivax and Plasmodium ovale. It is effective in preventing the relapse of these malaria species by eliminating the liver forms of the parasites. Chingamin (A) is not a commonly used drug for malaria prophylaxis. Pyrantel (B) is an anthelmintic drug used for treating parasitic worm infections, not malaria. Pyrimethamine (Chloridinum) (C) is primarily used in combination with sulfadoxine for treating uncomplicated malaria, not for chemoprophylaxis.
Question 6 of 9
Microscopic examination of pus sample taken from mandibular fistula canal and stained by Gram's method has revealed druses with gram-positive coloring in the center and cone-shaped structures with gram-negative coloring. Such morphology is characteristic of the agent of:
Correct Answer: B
Rationale: The correct answer is B: Actinomycosis. Actinomyces is a gram-positive bacterium that forms sulfur granules (druses) with gram-positive coloring in the center and filamentous structures resembling cones with gram-negative coloring. This morphology is characteristic of Actinomyces species. Fusobacteriosis (choice A) typically presents with gram-negative rods. Staphylococcal osteomyelitis (choice C) is caused by gram-positive staphylococci, not Actinomyces. Anaerobic infections (choice D) can be caused by various bacteria, but the specific morphology described in the question matches Actinomyces, making choice B the correct answer.
Question 7 of 9
A relationship in which one organism benefits and the other is harmed is called:
Correct Answer: B
Rationale: The correct answer is B: parasitism. In parasitism, one organism (parasite) benefits at the expense of the other organism (host). The parasite derives nutrients or resources from the host, causing harm or even death in some cases. This relationship is characterized by asymmetry, where one organism benefits while the other is negatively impacted. Commensalism (A) is a relationship where one organism benefits while the other is unaffected. Synergism (C) is a mutually beneficial relationship where both organisms benefit. Antagonism (D) is a relationship where both organisms are harmed or inhibited.
Question 8 of 9
The most common causative agent of bacterial meningitis are:
Correct Answer: B
Rationale: The correct answer is B because Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis are the most common causative agents of bacterial meningitis. Haemophilus influenzae is often seen in children, Streptococcus pneumoniae is the most common in adults, and Neisseria meningitidis is common in adolescents and young adults. Choice A is incorrect because although Streptococcus group B and Listeria monocytogenes can cause meningitis, E. Coli K1 is not a common causative agent. Choice C is incorrect because Staphylococcus aureus and Pseudomonas aeruginosa are not typically associated with bacterial meningitis. Choice D is incorrect as there are known causative agents for bacterial meningitis.
Question 9 of 9
Which of the following viruses has the name of the city where it was first discovered:
Correct Answer: B
Rationale: Step-by-step rationale: 1. Marburg virus is named after the German city Marburg where it was first identified in 1967. 2. Chikungunya virus is named after a village in Tanzania. 3. Measles virus got its name from the Middle English word "maselen" meaning "many little spots". 4. Epstein-Barr virus is named after Michael Epstein and Yvonne Barr, who discovered it. Summary: B is correct as it is directly named after the city of its discovery. A, C, and D are incorrect as they are named after other locations, characteristics, or discoverers.