A full-term infant presents with history of low birth weight, microcephaly, hepatosplenomegaly, and chorioretinitis; investigations reveals thrombocytopenia and abnormal liver enzymes; skull films revealed intracranial calcifications. Of the following, the MOST likely diagnosis is

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NCLEX Questions Pediatric Infectious Diseases Questions

Question 1 of 5

A full-term infant presents with history of low birth weight, microcephaly, hepatosplenomegaly, and chorioretinitis; investigations reveals thrombocytopenia and abnormal liver enzymes; skull films revealed intracranial calcifications. Of the following, the MOST likely diagnosis is

Correct Answer: C

Rationale: Microcephaly, hepatosplenomegaly, chorioretinitis, and calcifications in a term infant suggest CMV (C), the most common congenital infection, over others (A, B, D, E).

Question 2 of 5

The treatment of neonatal chlamydial conjunctivitis is

Correct Answer: A

Rationale: Neonatal chlamydial conjunctivitis requires oral erythromycin (A) to treat ocular and potential systemic infection, per standard protocols.

Question 3 of 5

The treatment of bronchopulmonary dysplasia (BPD) include all the following EXCEPT

Correct Answer: A

Rationale: BPD management includes hydration (B), steroids (C), ventilation (D), and RSV prophylaxis (E). Tracheotomy (A) is rare and not standard.

Question 4 of 5

A 40-day-old infant product of difficult vaginal delivery, presented with repeated vomiting, pallor, and recurrent seizures. On examination, occipitofrontal circumference was 41 cm. Lab study showed; Hb level, 7 gm/dl. You suspect intracranial hemorrhage. Of the following, the MOST likely site of hemorrhage is

Correct Answer: A

Rationale: Subdural hemorrhage (A) fits difficult delivery, late seizures, and anemia at 40 days, more than subarachnoid (B), periventricular (C), IVH (D), or intraparenchymal (E) in term infants.

Question 5 of 5

Early clinical sign of necrotizing enterocolitis (NEC) is

Correct Answer: D

Rationale: Abdominal distension (D) is the earliest NEC sign, reflecting bowel inflammation, per clinical staging.

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