A female who had been continuously taking antibiotics for an intestinal infection developed a complication manifested by inflammation of the oral mucosa and white deposit. Bacteriological study of the deposit samples revealed yeast fungi Candida albicans. Which of the following medications is indicated for the treatment of this complication?

Correct Answer: A

Rationale: Rationale for Correct Answer (A: Fluconazole): Fluconazole is an antifungal medication used to treat yeast infections caused by Candida albicans. It targets the fungal cell membrane, disrupting its structure and function. This makes it an effective treatment for oral thrush, which is caused by Candida overgrowth in the oral mucosa. The continuous use of antibiotics can disrupt the normal balance of microorganisms in the body, leading to fungal overgrowth. Fluconazole specifically targets the yeast fungi without affecting bacteria, making it the appropriate choice for this complication. Summary of Incorrect Choices: B: Biseptol - Biseptol is an antibiotic that targets bacteria, not fungi like Candida albicans. C: Tetracycline - Tetracycline is also an antibiotic that targets bacteria, not fungi. D: Furazolidone - Furazolidone is an antibiotic primarily used for treating bacterial infections, not fungal infections like oral thrush caused by Candida

Correct Answer: A

Rationale: The correct answer is A: Tryptic soy agar is a general-purpose medium suitable for cultivating a wide range of microorganisms. It provides essential nutrients for growth without inhibiting specific types of bacteria. Blood agar (B), Mannitol salt agar (C), and MacConkey agar (D) are selective or differential media designed to promote the growth of specific types of bacteria or differentiate between different bacterial species. Therefore, they are not considered general-purpose mediums.

Correct Answer: B

Rationale: The correct answer is B: Before antibiotic therapy is begun. Detecting penicillin-resistant, beta-lactamase-producing strains before antibiotic therapy is crucial to ensure proper treatment. If detected after therapy (choice A), it may lead to treatment failure. Detection during therapy (choice C) may result in delayed or ineffective treatment. Choice D is incorrect as early detection is essential for successful management.

Correct Answer: D

Rationale: The correct answer is D, All of the above. Clostridium botulinum produces botulinum toxin causing botulism, Vibrio cholerae produces cholera toxin leading to severe diarrhea, and certain strains of Escherichia coli produce toxins causing gastrointestinal illness. Each bacterium has specific exotoxins that can result in severe gastrointestinal symptoms. Therefore, all three choices are correct in producing exotoxins that can cause severe gastrointestinal illness.

Correct Answer: B

Rationale: The correct answer is B: Salmonella enterica. Typhoid fever is caused by the bacterium Salmonella enterica serotype Typhi. This specific strain of Salmonella is responsible for typhoid fever, a serious illness characterized by high fever, abdominal pain, and diarrhea. Escherichia coli (choice A) is not the causative agent of typhoid fever. Shigella flexneri (choice C) causes bacillary dysentery, not typhoid fever. Staphylococcus aureus (choice D) can cause food poisoning but is not associated with typhoid fever.

Correct Answer: A

Rationale: The correct answer is A: Late congenital syphilis. The symptoms described align with late congenital syphilis, which includes saddle nose, high-arched palate, natiform skull, peg-shaped incisors, and notched cutting edge. Lymph nodes not being affected is also consistent with late congenital syphilis. Early congenital syphilis (B) typically presents with more severe symptoms at birth or shortly after. Tertiary syphilis (C) usually occurs years after initial infection and presents with different symptoms. Fluorosis (D) is caused by excessive fluoride intake and does not match the symptoms described.

Correct Answer: A

Rationale: The correct answer is A: TRUE. Poxviruses are indeed the largest viruses, ranging from 200-450 nm in size, which is close to the resolution limit of a light microscope. This makes them almost visible under a light microscope. The other choices are incorrect because poxviruses are not smaller or uncertain in size (choices B and C), nor are they partially visible - they are almost visible due to their relatively large size.

Correct Answer: A

Rationale: The correct answer is A: cytomegalovirus. CMV is the most common virus transmitted during pregnancy, leading to potential serious complications for the fetus. It can cause birth defects, hearing loss, and developmental delays. CMV is commonly spread through bodily fluids. HIV (B) can also be transmitted during pregnancy but is less common. Herpes simplex virus (C) can be transmitted but typically results in localized infection. Epstein-Barr virus (D) is not commonly transmitted during pregnancy.

Correct Answer: A

Rationale: The correct answer is A: Corynebacterium diphtheriae. This bacterium produces the diphtheria toxin, which is responsible for causing diphtheria. The other choices, B, C, and D, are incorrect because Bacillus anthracis produces anthrax toxins, Clostridium tetani produces tetanus toxin, and Listeria monocytogenes does not produce the diphtheria toxin. Understanding the specific bacteria-toxin associations is crucial in correctly identifying the pathogen responsible for a particular disease.