ATI RN
Test Bank Pharmacology Questions
Question 1 of 5
A drug with a half life of 12 hours is administered by continuous intravenous infusion. How long will it take for the drug to reach 90% of its final steady-state level?
Correct Answer: C
Rationale: When a drug is administered by continuous intravenous infusion, it will take approximately 4-5 half-lives for it to reach 90% of its final steady-state level. In this case, the drug has a half-life of 12 hours, so it will take 4 half-lives (12 hours x 4 = 48 hours) for the drug to reach 90% of its final steady-state level. Therefore, the drug will reach 90% of its final steady-state level after 48 hours of continuous infusion.
Question 2 of 5
The labor and delivery nurse assists with the delivery of a newborn to a woman taking an adrenergic blocker for a congenital heart defect. What organ systems may be affected in the newborn by these drugs? (Select all that apply.)
Correct Answer: B
Rationale: Adrenergic blockers can affect labor, and babies born to mothers taking these drugs may exhibit adverse cardiovascular, respiratory, and CNS effects. Problems with the GI and GU systems have not been reported. The nurse should monitor the newborn for potential adverse effects and intervene as needed to ensure safety.
Question 3 of 5
A child is receiving methylphenidate. The mother tells the nurse the patient is having trouble sleeping while on the medication. What is the best response by the nurse?
Correct Answer: A
Rationale: Methylphenidate, a stimulant used to treat ADHD, can cause insomnia if taken too late in the day. Administering the medication earlier in the day (before 4:00 pm) can help minimize sleep disturbances. Giving it at 8:00 pm (B) would worsen insomnia. Stopping the medication abruptly (C) is not recommended without consulting the healthcare provider. Diphenhydramine (D) is not a solution for stimulant-induced insomnia.
Question 4 of 5
The client is about to start the treatment for juvenile rheumatoid arthritis. Before the administration of etanercept (Enbrel), it is important for the nurse to:
Correct Answer: A
Rationale: Etanercept is administered via injection, and some formulations may contain latex in the packaging or delivery system. Assessing for a latex allergy is crucial to prevent allergic reactions. While vaccinations and travel plans are important considerations, they are not as critical as ensuring the client's safety regarding potential allergens. Avoiding people who recently received etanercept is not a standard precaution.
Question 5 of 5
A 25-year-old woman suffers a bee sting and within a few minutes she notices a blotchy rash appearing on her body. She is taken to A&E where her BP is 90/60 mmHg. The most appropriate immediate therapy would be:
Correct Answer: D
Rationale: Anaphylaxis (rash, hypotension) post-bee sting needs urgent reversal. Oral antihistamine is too slow for systemic shock. IV adrenaline (1:10000) suits cardiac arrest, not initial anaphylaxis. IV hydrocortisone acts slowly, supporting later. IM adrenaline (0.5 mL 1:1000, 0.5 mg) rapidly reverses bronchospasm and hypotension via alpha/beta agonism, the immediate therapy per guidelines. Salbutamol targets asthma, not shock. IM adrenaline's speed saves lives in anaphylaxis.