ATI RN
ATI Pharmacology Practice Exam B Questions
Question 1 of 5
A drug that has both affinity and intrinsic activity
Correct Answer: D
Rationale: A drug that has both affinity and intrinsic activity is known as a partial agonist. Affinity refers to the drug's ability to bind to a receptor, while intrinsic activity is the drug's ability to activate the receptor and produce a response. A partial agonist binds to the receptor with affinity but only activates the receptor to a partial extent compared to a full agonist. This results in a less potent response compared to a full agonist but also blocks the full agonist's effects, making it act as an antagonist in the presence of a full agonist. In summary, a drug that has both affinity and intrinsic activity is classified as a partial agonist because it binds to the receptor and activates it but to a lesser extent than a full agonist.
Question 2 of 5
The nurse assumes care of a patient in the post-anesthesia care unit (PACU). The patient had abdominal surgery and is receiving intravenous morphine sulfate for pain. The patient is asleep and has not voided since prior to surgery. The nurse assesses a respiratory rate of 10 breaths per minute and notes hypoactive bowel sounds. The nurse will contact the surgeon primarily to report which condition?
Correct Answer: B
Rationale: The most critical condition that the nurse should report to the surgeon in this scenario is respiratory depression. Respiratory depression is a potential side effect of opioid medications such as morphine sulfate. It is characterized by a decreased respiratory rate, which in this case, is 10 breaths per minute, indicating inadequate ventilation. Respiratory depression can lead to hypoxia and respiratory arrest if not promptly addressed. The nurse should prioritize notifying the surgeon to ensure immediate intervention and appropriate monitoring to prevent further complications for the patient. While the other conditions (paralytic ileus, somnolence, and urinary retention) are also relevant to the patient's care, respiratory depression poses the most immediate threat to the patient's safety and requires urgent attention.
Question 3 of 5
Which action is most important for the nurse to teach a patient who is taking tositumomab?
Correct Answer: C
Rationale: Tositumomab is a radioactive monoclonal antibody used in cancer treatment. Patients should be advised to use a separate bathroom and sit while urinating to minimize radiation exposure to others and themselves. This precaution is necessary because the drug is excreted in urine, which remains radioactive for a period after treatment. Avoiding alcohol or smoking is not specifically related to tositumomab therapy. Taking the drug on an empty stomach is not applicable, as it is administered intravenously.
Question 4 of 5
A patient being seen for skin concerns asks, 'What do keratolytic drugs remove?' What is the nurse’s best response?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
The nurse is reviewing new medication orders that have been written for a newly admitted patient. The nurse will need to clarify which orders? Select all that apply.
Correct Answer: D
Rationale: Medication orders must be clear, complete, and appropriate for the patient's condition. Orders that include 'as needed' (PRN) medications, such as 'Docusate (Colace) as needed for constipation,' require clarification because they lack specific dosing instructions. The nurse must confirm the frequency, dosage, and indications for PRN medications to ensure safe administration. The other orders (Metformin, Sitagliptin, Simvastatin, and Irbesartan) are complete and do not require clarification. Therefore, the nurse should focus on clarifying the PRN order to avoid errors in medication administration.