A drug for which research has shown an adverse effect in animals but not in pregnant women would be categorized as Category

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ATI Pharmacology Book Questions

Question 1 of 5

A drug for which research has shown an adverse effect in animals but not in pregnant women would be categorized as Category

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

A 17-year-old man is brought to the emergency department with severe right lower quadrant pain that he first felt around his umbilicus. His white blood cell count is 12,000/μL of blood. He is taken to the operating room for emergent laparoscopic appendectomy. About an hour into the surgery, his body temperature spikes and CO2 production rises uncontrollably. What is the next step in the treatment of this patient?

Correct Answer: C

Rationale: Fever and CO2 rise during surgery suggest malignant hyperthermia (MH). Dantrolene , a ryanodine receptor antagonist, halts MH by blocking calcium release. Acetaminophen reduces fever but not MH. Bromocriptine treats neuroleptic syndrome. Diazepam and Naproxen (E) are irrelevant. Dantrolene's specificity saves lives in this surgical emergency.

Question 3 of 5

A 19-year-old female is brought to the emergency department by a friend concerned with a change in her behavior during a party. The patient is agitated, anxious, and exhibits paranoid reactions to the physical exam. Her pulse is 120 beats/minute and her blood pressure is 150/100 mm Hg. She also complains of 'bugs' crawling all over her skin, although there is nothing there. Which of the following drugs has she most likely taken?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

A 21-year-old male college student presents to the emergency department with hives over his chest and arms. The history and physical exam reveals that he used a new laundry detergent and he was having an allergic reaction. The physician wants to prescribe an antihistamine that will not sedate the patient because he has to study for a test. What is the most appropriate treatment?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

A 30-year-old male patient who is treated with haloperidol for his diagnosis of schizophrenia is considered to be well-managed symptomatically for his psychotic symptoms. However, he is reporting restlessness, the inability to sit still at the dinner table, and his family notices that he is pacing up and down the hallway frequently. Of the following, which is the best medication to treat this antipsychotic-induced akathisia?

Correct Answer: E

Rationale: Haloperidol's D2 blockade causes akathisia—restlessness and pacing—as an EPS. Propranolol, a beta-blocker, reduces akathisia by modulating catecholamine activity, a first-line treatment per guidelines, unlike anticholinergics (benztropine) which target dystonia/parkinsonism. Dantrolene treats muscle spasticity, not akathisia. Amoxapine, an antidepressant, worsens psychosis. Bromocriptine, a dopamine agonist, risks psychosis exacerbation. Propranolol's efficacy, safety, and specificity for akathisia make it the best choice, replacing D as instructed.

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