ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
A cluster of genes that encode proteins
Correct Answer: C
Rationale: MHC is a gene cluster encoding proteins for antigen presentation, distinct from BCR and TCR genes.
Question 2 of 5
The aim of monoclonal antibody production is to produce cells that only secrete immunoglobulin directed against the antigen used in immunization. Which of the following hybridoma production steps is NOT correct?
Correct Answer: C
Rationale: Selective medium (e.g., HAT) allows only fused hybridoma cells to survive, not non-fused cells, making c incorrect.
Question 3 of 5
Has different subtypes
Correct Answer: A
Rationale: IgG has subtypes (e.g., IgG1, IgG2), unlike IgM or IgE.
Question 4 of 5
Penicillin can form a hapten-carrier conjugate with a self-protein that can then act as an immunogen and generate an immunoglobulin antibody, and can cross-react with a number of other antibiotics. This can complicate the treatment of bacterial infections in these patients because they are unable to take the antibiotics necessary to combat the infection.
Correct Answer: C
Rationale: This describes an IgE-mediated allergic response, where penicillin cross-reacts, causing hypersensitivity.
Question 5 of 5
Each polypeptide chain (heavy and light) on immunoglobulin has a variable (V) and constant (C) region. Immunoglobulin chains are encoded by that is/are rearranged during development to assemble a functional gene encoding either a heavy or a light chain.
Correct Answer: C
Rationale: Immunoglobulin genes in B cells are encoded by sets of V, D, and J gene segments that rearrange during development.