ATI RN
Proctored Pharmacology ATI Questions
Question 1 of 5
A client with Parkinson's disease is prescribed levodopa/carbidopa (Sinemet). Which instruction should the nurse include?
Correct Answer: C
Rationale: Levodopa/carbidopa treats Parkinson's by increasing dopamine, but vasodilation risks orthostatic hypotension. Rising slowly prevents falls, a key instruction for safety. High-protein meals reduce levodopa absorption via amino acid competition, decreasing efficacy. Dark urine isn't a typical concern'harmless pigment changes occur. Stopping if feeling better risks symptom return, as it's not a cure. Rising slowly aligns with the drug's side effect profile, critical in Parkinson's where mobility is impaired, making C the essential teaching point to ensure client stability and adherence.
Question 2 of 5
The following drugs can cause QT prolongation:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
What is the correct definition of drug absorption?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following is the antidote for Heparin?
Correct Answer: A
Rationale: Protamine sulfate is the antidote for Heparin. Heparin is an anticoagulant used to prevent blood clotting. Protamine sulfate works by binding to heparin, neutralizing its anticoagulant effects. Vitamin K is not the antidote for Heparin; it is used to reverse the effects of warfarin, another type of anticoagulant. Naloxone is an opioid antagonist used to reverse the effects of opioids, and Toradol is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief.
Question 5 of 5
Which drug undergoes extensive first-pass hepatic metabolism?
Correct Answer: C
Rationale: Propranolol undergoes extensive first-pass metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration.