ATI RN
Virtual ATI Pharmacology Assessment Questions
Question 1 of 5
A client with osteoporosis is prescribed alendronate (Fosamax). Which instruction should the nurse include?
Correct Answer: A
Rationale: Alendronate, a bisphosphonate, treats osteoporosis but risks esophageal irritation. Taking it with water and staying upright prevents reflux, ensuring safety and absorption. With meals reduces uptake via calcium binding. Crushing increases irritation risk. Bedtime heightens reflux. This instruction aligns with alendronate's administration guidelines, critical in osteoporosis where adherence prevents fractures, making A the key teaching point.
Question 2 of 5
Which of the following drugs is contraindicated if there is a history of acute porphyria?
Correct Answer: C
Rationale: Acute porphyria involves heme synthesis defects, triggered by drugs inducing hepatic enzymes (e.g., CYP450). Quinine, used in malaria, isn't a major porphyria trigger. Atenolol, a beta-blocker, is porphyrin-safe, with minimal enzyme induction. Oral contraceptives, containing estrogens/progestins, induce ALA synthase, exacerbating acute porphyria, making them contraindicated. Heparin and amoxicillin don't significantly affect porphyrin metabolism. The contraceptive link reflects hormonal exacerbation of porphyric attacks, critical for safe prescribing in this rare condition.
Question 3 of 5
A 28-year-old woman presents to the emergency department in an acute asthma exacerbation. Her asthma developed in her 20s after she had recurrent upper respiratory infections. She was doing well, but she twisted her ankle yesterday and was taking aspirin to reduce the inflammation. She is diagnosed with aspirin-induced asthma. What is the most appropriate long-term treatment for her condition?
Correct Answer: D
Rationale: Aspirin-induced asthma (AIA) involves leukotriene overproduction. Zafirlukast , a leukotriene receptor blocker-prevents attacks long-term. Albuterol and Ipratropium treat acutely. Cromolyn stabilizes mast cells but is less specific. Theophylline (E) is outdated. Zafirlukast targets AIA's pathophysiology.
Question 4 of 5
Advise patient to avoid taking antacids or antidiarrheals for how long after taking digoxin?
Correct Answer: C
Rationale: Antacids or antidiarrheals should be avoided for at least 4 hours after taking digoxin. These medications can interfere with the absorption of digoxin in the body, thereby reducing its effectiveness. By spacing out the administration of these medications, the risk of decreased digoxin absorption and potential impact on its therapeutic effects can be minimized. It is important for patients to follow this guidance to ensure optimal effectiveness of digoxin therapy.
Question 5 of 5
A client with osteoporosis is prescribed alendronate (Fosamax). Which instruction should the nurse include?
Correct Answer: A
Rationale: Alendronate, a bisphosphonate, treats osteoporosis but risks esophageal irritation. Taking it with water and staying upright prevents reflux, ensuring safety and absorption. With meals reduces uptake via calcium binding. Crushing increases irritation risk. Bedtime heightens reflux. This instruction aligns with alendronate's administration guidelines, critical in osteoporosis where adherence prevents fractures, making A the key teaching point.