A client with HIV is beginning therapy with zidovudine. The nurse should monitor the client for which of the following adverse effects of this medication?

Correct Answer: A

Rationale: Fatigue is a common adverse effect of zidovudine due to its impact on bone marrow, leading to anemia. Zidovudine is known to suppress bone marrow function, resulting in decreased production of red blood cells and subsequently causing fatigue due to anemia. Monitoring for fatigue is essential to ensure early detection and management of this adverse effect.

Correct Answer: A

Rationale: In this scenario, the correct adverse effect that the nurse should instruct the client to monitor when starting therapy with filgrastim is bone pain (Option A). Filgrastim is a medication that stimulates the production of white blood cells, specifically neutrophils, and bone pain is a common side effect associated with its use. Option B, constipation, is not typically associated with filgrastim therapy. Option C, tinnitus, is a symptom related to the ears and is not a common adverse effect of filgrastim. Option D, dry mouth, is also not a common adverse effect of filgrastim. In an educational context, it is essential for nurses to understand the expected adverse effects of medications to educate and monitor patients effectively. By teaching clients about potential side effects like bone pain with filgrastim, nurses empower them to recognize and report these symptoms promptly, leading to better management of their medication therapy. This knowledge also enhances patient safety and compliance with treatment regimens.

Correct Answer: C

Rationale: In this scenario, the correct answer is C) Neutropenia. Neutropenia is a common side effect of hydroxyurea, which is a myelosuppressive agent commonly used in the treatment of chronic myeloid leukemia. Neutropenia refers to a decreased level of neutrophils, which are crucial in fighting off infections. Therefore, monitoring for neutropenia is essential to prevent the risk of infections in the client. Option A) Hyperkalemia is not typically associated with hydroxyurea therapy, so this finding is less relevant in this context. Option B) Hypertension is not a common side effect of hydroxyurea and is not directly related to its mechanism of action or therapeutic effects in chronic myeloid leukemia. Option D) Tinnitus is not a typical side effect of hydroxyurea and is not a priority finding when monitoring a client receiving this medication for chronic myeloid leukemia. Understanding the side effects and monitoring parameters associated with specific medications is crucial for nurses caring for clients receiving these treatments. Close monitoring and early recognition of potential side effects can help in providing safe and effective care to clients undergoing pharmacological treatments for various conditions.

Correct Answer: C

Rationale: The correct answer is C: Neutropenia. Paclitaxel commonly causes neutropenia due to bone marrow suppression. It is essential for clients receiving this medication to monitor for signs of neutropenia, such as fever, chills, and increased susceptibility to infections, as it can increase the risk of serious complications.

Correct Answer: A

Rationale: Etoposide is associated with hypotension as a common adverse effect. Therefore, the nurse should closely monitor the client for signs and symptoms of hypotension while receiving this medication, such as dizziness, light-headedness, or low blood pressure readings. Prompt recognition and management of hypotension can help prevent complications and ensure the client's safety during treatment with etoposide.