Correct Answer: C

Rationale: The correct answer is C. Taking aspirin along with Warfarin can increase the risk of bleeding. Clients should be advised to avoid medications that increase the risk of bleeding when taking Warfarin to prevent complications.

Correct Answer: A

Rationale: An INR of 4.0 indicates that the client's blood is clotting too slowly, increasing the risk of bleeding. This level is above the therapeutic range for a client on Warfarin therapy. Therefore, the healthcare professional should notify the provider immediately to prevent potential bleeding complications.

Correct Answer: B

Rationale: It is crucial to rotate the application site daily when using nitroglycerin patches to prevent skin irritation and ensure optimal absorption of the medication.

Correct Answer: A

Rationale: The therapeutic effect of lisinopril, an ACE inhibitor, is indicated by a decrease in blood pressure. Lisinopril works by relaxing blood vessels, leading to a reduction in blood pressure. Monitoring and achieving a decrease in blood pressure is a key outcome when managing hypertension with lisinopril.

Correct Answer: D

Rationale: The expected outcome of Valproate therapy is a decrease in seizure activity. Valproate is commonly used in the treatment of epilepsy to help control and reduce seizure frequency.