A client is prescribed with Pentamidine (Pentam) IV for the treatment of Pneumocystis carinii

Correct Answer: D

Rationale: A sudden increase in temperature in a client receiving Pentamidine IV for the treatment of Pneumocystis carinii is most likely an indication that the client has developed another infection. Pentamidine is an antiparasitic medication used to treat Pneumocystis carinii pneumonia in immunocompromised individuals such as those with HIV/AIDS. An increase in temperature could be a sign of a new or worsening infection, especially in patients who are already immunocompromised. It is important for the nurse to monitor the client closely for signs of infection and notify the healthcare provider if there are any concerning symptoms.

Correct Answer: D

Rationale: Androgen therapy, typically testosterone, aims to increase libido and treat erectile dysfunction in men with hypogonadism, restoring sexual drive. Decreasing libido opposes its intent. It doesn't release FSH or increase LH-exogenous testosterone suppresses these via feedback. Boosting libido corrects deficiency symptoms, improving quality of life, a primary clinical goal.

Correct Answer: D

Rationale: Acute asthma and pneumonia in pregnancy require urgent care. IV crystalloids rehydrate, safe and necessary. High FiO2 (40%) supports oxygenation in asthma/pneumonia, appropriate. Nebulized salbutamol, a beta-agonist, relieves bronchospasm, standard and safe. IV hydrocortisone reduces inflammation, suitable. IV gentamicin, an aminoglycoside, treats pneumonia but is inappropriate due to cephalosporin cross-reactivity risk (angioedema history) and fetal ototoxicity concerns, making it unsafe here. Alternative antibiotics (e.g., macrolides) are preferred, prioritizing maternal and fetal safety.

Correct Answer: B

Rationale: Levodopa treats Parkinson's by crossing the blood-brain barrier and converting to dopamine, but peripheral metabolism by dopa decarboxylase reduces its availability and causes side effects like nausea. Carbidopa, a peripheral dopa decarboxylase inhibitor, doesn't cross into the CNS, so it prevents levodopa breakdown outside the brain, increasing its CNS entry and efficacy. It doesn't stimulate dopamine receptors—levodopa's metabolite does that. Absorption isn't directly enhanced; bioavailability improves due to less peripheral loss. Peripheral dopamine production decreases with carbidopa, not increases, reducing side effects. COMT inhibition (e.g., entacapone) is a separate strategy. By blocking peripheral conversion, carbidopa ensures more levodopa reaches the brain, optimizing therapy and minimizing adverse effects.

Correct Answer: A

Rationale: Rifampicin is a potent inducer of CYP450 enzymes, increasing the metabolism of drugs processed via these pathways.