ATI RN
ATI Pharmacology Online Practice 2023 A Questions
Question 1 of 5
A client is prescribed with carbamazepine (Tegretol) for the treatment of bipolar disorder. Which of the following laboratory results indicates that the client is experiencing a side effect of this medication?
Correct Answer: A
Rationale: Carbamazepine can cause leukopenia, including neutropenia, as a side effect. A neutrophil count of 1,200/mm3 is below the normal range and indicates a potential adverse effect. Platelet count, uric acid, and SGPT levels are within normal ranges and do not indicate side effects. Therefore, the neutrophil count is the concerning result.
Question 2 of 5
Which of the following antiparkinsonian drugs may cause vasospasm?
Correct Answer: B
Rationale: Bromocriptine, a dopamine D2 agonist used in Parkinson's, has ergot alkaloid properties, which can cause vasospasm by stimulating vascular smooth muscle receptors, occasionally leading to Raynaud's-like symptoms or digital ischemia. Amantadine, an NMDA antagonist, enhances dopamine release but lacks vasoconstrictive effects. Carbidopa inhibits dopa decarboxylase, aiding levodopa delivery without vascular impact. Entacapone, a COMT inhibitor, extends levodopa's duration but doesn't affect vessels. Ropinirole, a non-ergot agonist, avoids vasospasm. Bromocriptine's ergot-derived vasoconstriction, though rare, distinguishes it among antiparkinsonian drugs, requiring caution in patients with vascular risks.
Question 3 of 5
The following drugs can induce malignant hyperthermia:
Correct Answer: B
Rationale: Succinylcholine is a trigger for malignant hyperthermia in susceptible individuals due to its effects on calcium release in muscle cells.
Question 4 of 5
What is the most life threatening adverse reaction while taking Omeprazole?
Correct Answer: D
Rationale: Acute interstitial nephritis is a rare but serious adverse reaction associated with omeprazole. It is characterized by inflammation of the kidney's interstitial tissue and can lead to kidney dysfunction. Symptoms may include fever, rash, eosinophilia, and impaired renal function. If left untreated, acute interstitial nephritis can progress to acute kidney injury and potentially be life-threatening. Therefore, it is essential to promptly recognize and manage this adverse reaction when taking omeprazole.
Question 5 of 5
A 33-year-old man with a history of asthma comes into the emergency department after getting stung by a bee. The treating physician wants to give epinephrine subcutaneously. Which of the following contraindications to this medication is noted?
Correct Answer: B
Rationale: Epinephrine treats anaphylaxis but risks exacerbating narrow-angle glaucoma . It dilates pupils, increasing intraocular pressure. Diabetes , pulmonary failure , thyroid disease , and age (E) aren't absolute contraindications. Glaucoma's risk requires caution in this asthmatic.