Correct Answer: D

Rationale: Acarbose, used for type 2 Diabetes Mellitus, can lead to liver toxicity with long-term use. Therefore, monitoring liver function tests periodically is essential to detect any signs of liver dysfunction early and prevent complications.

Correct Answer: C

Rationale: The correct way to administer eye drops is by instructing the client to drop the prescribed amount of medication into the center of the conjunctival sac. This technique helps in proper distribution and absorption of the medication.

Correct Answer: D

Rationale: The correct answer is 'Orthostatic hypotension.' Amitriptyline can lead to orthostatic hypotension, a sudden drop in blood pressure when standing up, which can cause dizziness and increase the risk of falls. It is crucial for the nurse to monitor the client for signs of orthostatic hypotension, such as dizziness or lightheadedness when changing positions, and to educate the client to move slowly when transitioning from lying or sitting to standing.

Correct Answer: D

Rationale: Metformin is known to potentially cause lactic acidosis, especially in patients with impaired renal function. Monitoring serum creatinine levels is essential for assessing kidney function and detecting any adverse effects of Metformin on renal health.

Correct Answer: C

Rationale: Ezetimibe is contraindicated in patients with active moderate-to-severe liver disorders, such as active hepatitis C, especially when they are already taking a statin like simvastatin. This combination can increase the risk of liver problems and is not recommended due to the potential for further liver damage.