Correct Answer: A

Rationale: St. John's wort should be avoided by clients taking Warfarin as it can reduce the medication's effectiveness. The nurse should also advise the client to avoid other supplements that may interact with Warfarin, such as garlic and ginseng.

Correct Answer: C

Rationale: Methylnaltrexone is an opioid antagonist used to treat severe constipation unrelieved by laxatives in opioid-dependent clients. It blocks the mu opioid receptors in the GI tract, helping to alleviate constipation without affecting pain relief or causing withdrawal symptoms.

Correct Answer: C

Rationale: The correct answer is C. Erythromycin should be taken on an empty stomach with a full glass of water to increase absorption. Taking it with milk (choice A) or an antacid (choice D) can interfere with its absorption. Avoiding direct sunlight (choice B) is not directly related to the administration of erythromycin.

Correct Answer: A

Rationale: To determine the flow rate in drops per minute (gtt/min), you can use the formula: (Volume in mL x Drop factor) / Time in minutes = Flow rate in gtt/min. In this case, it would be (100 mL x 10 gtt/mL) / 45 min = 22 gtt/min. Therefore, the healthcare professional should adjust the manual IV infusion to deliver 22 gtt/min.

Correct Answer: A

Rationale: Orthostatic hypotension is a known adverse effect of Phenelzine, a monoamine oxidase inhibitor (MAOI) used for depression. It is caused by a sudden drop in blood pressure when changing positions, leading to symptoms like dizziness or fainting. Monitoring for orthostatic hypotension is crucial during Phenelzine therapy to prevent complications.