A client has a new prescription for levothyroxine. Which of the following instructions should the nurse include?

Correct Answer: C

Rationale: In pharmacology, understanding the administration of medications is crucial for their efficacy. In the case of levothyroxine, the correct instruction for the client is to take the medication on an empty stomach in the morning (Option C). Levothyroxine is a synthetic form of the thyroid hormone T4, and it is best absorbed when taken on an empty stomach, at least 30 minutes to 1 hour before breakfast. This ensures optimal absorption and effectiveness of the medication. Option A (take this medication at bedtime) is incorrect because it contradicts the need for an empty stomach for optimal absorption. Taking levothyroxine at bedtime may result in decreased absorption due to food interference. Option B (take this medication with food) is incorrect because, as mentioned earlier, levothyroxine should be taken on an empty stomach to prevent interactions with food that may hinder its absorption. Option D (take this medication with an antacid) is also incorrect because antacids can interfere with the absorption of levothyroxine by binding to the medication and reducing its effectiveness. Educationally, understanding the specific administration instructions for different medications is essential for safe and effective patient care. It is important for nurses to educate clients on the proper administration of medications like levothyroxine to ensure optimal therapeutic outcomes.

Correct Answer: B

Rationale: Isosorbide is an organic nitrate used to manage angina. Concurrent use of sildenafil with organic nitrates, like isosorbide, is contraindicated due to the risk of fatal hypotension. It is essential for clients to avoid taking nitrate medications within 24 hours of using isosorbide to prevent serious complications.

Correct Answer: B

Rationale: In this scenario, the correct answer is B) The subcutaneous site for redness following injection. Adalimumab is typically administered via subcutaneous injection for the treatment of Rheumatoid Arthritis. Monitoring the injection site for redness is crucial as it can indicate local inflammation or an allergic reaction, which are important considerations in the management of the medication. Option A) is incorrect as Adalimumab is not administered intravenously, so monitoring the vein for thrombophlebitis is not relevant. Option C) is incorrect as Adalimumab is not administered orally, so monitoring the oral mucosa for ulceration is not necessary. Option D) is incorrect as Adalimumab is not administered via a transdermal patch, so monitoring the skin for irritation following patch removal is not applicable. In an educational context, understanding the route of administration of medications is vital for nursing practice to ensure safe and effective patient care. Monitoring for and recognizing potential side effects or complications associated with specific routes of administration is essential in providing quality nursing care and promoting positive patient outcomes.

Correct Answer: B

Rationale: In this scenario, the correct medication to anticipate administering to a young adult client with a serum calcium level of 8.8 mg/dL is option B) Calcium carbonate. Calcium carbonate is a common treatment for hypocalcemia, which is characterized by low serum calcium levels. It works by providing supplemental calcium to raise the serum levels back to normal. In this case, the client's low serum calcium level indicates a need for a calcium supplement like calcium carbonate. The other options are not appropriate for a client with low serum calcium. A) Calcitonin-salmon is used to treat hypercalcemia (high serum calcium levels) by inhibiting bone resorption. C) Zoledronic acid and D) Ibandronate are both bisphosphonates used in the treatment of osteoporosis by inhibiting bone breakdown, not for increasing serum calcium levels. In an educational context, understanding the rationale behind choosing the correct medication based on the client's condition is crucial for safe and effective pharmacological interventions. It also highlights the importance of assessing and interpreting lab values to guide medication choices in clinical practice.

Correct Answer: D

Rationale: In severe Aspirin toxicity, respiratory depression is an anticipated finding due to the development of respiratory acidosis. Aspirin toxicity can lead to metabolic acidosis, causing the individual to hyperventilate initially to compensate. However, as the condition progresses, respiratory depression can occur, resulting in impaired gas exchange and respiratory acidosis.