Correct Answer: D

Rationale: The correct instruction for the client who has a new prescription for Levothyroxine to treat hypothyroidism is not to discontinue the medication without consulting the provider. Abrupt cessation could lead to the return of hypothyroid symptoms, emphasizing the importance of medical guidance when considering any changes to the treatment plan.

Correct Answer: A

Rationale: Protamine sulfate is the specific antidote for Heparin. Heparin is an anticoagulant medication used to prevent blood clots, and in cases of overdose or excessive bleeding, protamine sulfate is administered to reverse its effects by neutralizing heparin's anticoagulant activity.

Correct Answer: D

Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment.

Correct Answer: B

Rationale: The correct instruction for a client taking Acyclovir is to increase fluid intake during therapy. Acyclovir can cause nephrotoxicity, potentially leading to kidney damage. Increasing fluid intake helps prevent this adverse effect by promoting adequate renal function and drug elimination.

Correct Answer: A

Rationale: A common side effect of Albuterol is paradoxical bronchospasm, a condition where the airways become more constricted instead of relaxing, which can be a serious adverse reaction to the medication.