A chronic localized subcutaneous infection characterized by verrucoid lesions on the skin is:

Correct Answer: D

Rationale: The correct answer is D, chromoblastomycosis. This is a chronic localized subcutaneous infection caused by certain fungi, resulting in verrucoid lesions on the skin. The other choices are incorrect because: A: Candidiasis is a superficial fungal infection, not characterized by verrucoid lesions. B: Leprosy is a systemic bacterial infection, not localized to the skin with verrucoid lesions. C: Shingles is caused by the varicella-zoster virus, presenting as a painful rash with blisters, not verrucoid lesions.

Correct Answer: A

Rationale: The correct answer is A: Sabouraud. Sabouraud agar is specifically designed to promote the growth of fungi due to its low pH and high glucose content. The cream-like colonies indicate fungal growth, as fungi often appear as fluffy or powdery colonies on Sabouraud agar. Lowenstein-Jensen is used for mycobacteria, Roux for diphtheria, and Loeffler for Corynebacterium diphtheriae. Therefore, Sabouraud is the most suitable medium for detecting fungal contamination based on the characteristics of the colonies formed.

Correct Answer: D

Rationale: The correct answer is D, All of these. Orthopoxvirus genus includes Vaccinia, Smallpox, and Cowpox viruses. They share similar characteristics such as brick-shaped virions and double-stranded DNA genomes. Vaccinia virus is used in smallpox vaccine, Smallpox virus caused the eradicated disease, and Cowpox virus can infect both animals and humans. Therefore, all three viruses belong to the Orthopoxvirus genus. Choices A, B, and C are incorrect because they each represent a different virus from the genus Orthopoxvirus.

Correct Answer: C

Rationale: The correct answer is C: leg swelling. Endocarditis is an infection of the inner lining of the heart chambers and valves. Symptoms typically include fever, chills, weight loss, and muscle aches due to the body's immune response to the infection. Leg swelling is not a common symptom of endocarditis. It may occur in conditions like heart failure but is not directly associated with endocarditis. Therefore, choice C is the correct answer. Choices A, B, and D are incorrect because fever and chills, weight loss, and muscle aches are commonly seen in endocarditis due to the systemic inflammatory response to the infection.

Correct Answer: B

Rationale: The correct answer is B: Quorum sensing in bacteria refers to a process of cell-cell communication. Bacteria release signaling molecules to communicate with each other, coordinating group behaviors such as biofilm formation or virulence factor production when a certain population density is reached. This communication helps bacteria respond collectively to environmental cues. A: Incorrect - Locomotion refers to movement, not communication between bacteria. C: Incorrect - Uptake of foreign DNA is related to genetic transfer mechanisms, not communication. D: Incorrect - Antibiotic resistance mechanisms may involve genetic changes but are not directly related to inter-bacterial communication. In summary, quorum sensing is a vital communication system that allows bacteria to coordinate behaviors for survival and adaptation.

Correct Answer: D

Rationale: The correct answer is D, "All of the above," because all three bacteria (Salmonella enterica, Clostridium botulinum, Escherichia coli) are known to cause foodborne illnesses. Salmonella causes symptoms like diarrhea, fever, and abdominal cramps. Clostridium botulinum produces a toxin leading to botulism, a severe illness affecting the nervous system. Escherichia coli strains like E. coli O157:H7 can cause food poisoning with symptoms such as bloody diarrhea. Therefore, all the listed bacteria can cause foodborne illnesses due to their ability to contaminate food and infect individuals.

Correct Answer: A

Rationale: The correct answer is A: A vaccine strain. Virus Fixe is a specific strain of rabies virus used in the production of rabies vaccines. This strain has been attenuated to be safe for use in vaccines. Choice B, a cell culture, is incorrect as it does not specifically refer to Virus Fixe. Choice C, a wild type of rabies virus, is incorrect as Virus Fixe is not a wild type but a modified strain. Choice D, an infectious disease, is incorrect as Virus Fixe is not a disease but a strain of virus used in vaccines.

Correct Answer: A

Rationale: The most probable diagnosis is Tetanus (Choice A) based on the symptoms described. Tetanus is characterized by muscle stiffness, difficulty opening the mouth (trismus), muscle spasms, and convulsions. The progression of symptoms from muscle tension to generalized convulsions every 10-15 min is classic for tetanus. Tetania (Choice B) is similar but typically presents with more subtle muscle contractions rather than convulsions. Meningoencephalitis (Choice C) presents with fever, headache, and altered mental status, not the muscle symptoms described. Hemorrhagic stroke (Choice D) presents with sudden onset neurological deficits like weakness or sensory changes, not the muscle symptoms described.

Correct Answer: A

Rationale: Step 1: Understand haematogenic spread means bacteria traveling through blood. Step 2: Urinary tract infections typically occur due to bacteria entering through urethra, not via blood. Step 3: Choice A states bacterial UTIs are usually after haematogenic spread, which is incorrect. Step 4: Therefore, Choice A is NOT true for UTIs. Summary: B, C, and D are incorrect as they align with typical characteristics of UTIs.