Questions 9

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microbiology chapter 13 test bank Questions

Question 1 of 5

A child is ill with diphtheria. A smear of the affected mucous membrane revealed blue rods with thickenings at the poles. What staining method was used?

Correct Answer: A

Rationale: The correct answer is A: Neisser staining method. Neisser staining method is used to stain diphtheria bacilli, which appear as blue rods with thickenings at the poles. The rationale is that Neisser staining specifically targets and highlights the characteristics of the diphtheria bacilli. Incorrect choices: B: Gram staining is not specific for diphtheria bacilli and does not show the characteristic blue rods with thickenings at the poles. C: Ziehl-Neelsen staining is used for acid-fast bacteria like Mycobacterium tuberculosis, not for diphtheria bacilli. D: Loeffler staining is used for diphtheria bacilli but does not produce blue rods with thickenings at the poles as seen in this case.

Question 2 of 5

Rotaviruses:

Correct Answer: A

Rationale: The correct answer is A because the NSP4 nonstructural protein of rotaviruses indeed acts in a toxic-like manner by disrupting calcium homeostasis, leading to diarrhea. Choice B is incorrect as rotaviruses can cause significant disease in infants, but not typically in adults. Choice C is incorrect as rotaviruses are resistant to stomach acid. Choice D is incorrect as rotaviruses cause a net secretion of water and loss of ions, contributing to diarrhea.

Question 3 of 5

A 10 year old child was subjected to Mantoux test (with tuberculin). 48 hours later a papule up to 8 mm in diameter appeared on the site of tuberculin injection. What type of hyperesponsiveness reaction has developed after tuberculin injection?

Correct Answer: A

Rationale: The correct answer is A: Hyperresponsiveness reaction type IV. This type of reaction, also known as delayed-type hypersensitivity, is characterized by the activation of T lymphocytes and macrophages, leading to inflammation at the site of antigen exposure. In the case of the Mantoux test, the appearance of a papule 48 hours later indicates a delayed hypersensitivity reaction mediated by T cells. Choice B: Reaction of Arthus phenomenon type is incorrect as this type of reaction involves immune complexes forming in the blood vessels leading to tissue damage, which is not the mechanism seen in the Mantoux test reaction. Choice C: Reaction of serum sickness type is incorrect as this type of reaction involves the formation of immune complexes in the blood leading to systemic symptoms like fever, rash, and joint pain, which is not typically seen in the Mantoux test reaction. Choice D: Atopic reaction is incorrect as atopic reactions involve IgE antibodies and mast cell degranulation, which are not the mechanisms

Question 4 of 5

For prevention of tuberculosis is used

Correct Answer: B

Rationale: The correct answer is B: BCG. Bacille Calmette-Guérin (BCG) vaccine is used for the prevention of tuberculosis. BCG is a live attenuated strain of Mycobacterium bovis that helps the immune system recognize and fight off tuberculosis bacteria. Specific anti-tuberculosis serum (A) is not used for prevention but for treatment. DTP (C) stands for diphtheria, tetanus, and pertussis vaccine, not specific for tuberculosis prevention. PPD (D) is a tuberculin skin test used for diagnosis, not prevention. Thus, BCG is the correct choice for tuberculosis prevention.

Question 5 of 5

A patient with a sore throat and fever had a throat smear stained with Gram's method, revealing Gram-positive cocci in chains. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. This bacterium is known to cause sore throat and fever, commonly referred to as strep throat. Gram's stain showing Gram-positive cocci in chains is characteristic of Streptococcus species. Streptococcus pyogenes is a beta-hemolytic bacterium that forms chains and is a common cause of bacterial pharyngitis. Staphylococcus aureus (B) is a Gram-positive cocci that forms clusters, not chains. Neisseria gonorrhoeae (C) is a Gram-negative diplococcus and is not associated with sore throat. Enterococcus faecalis (D) is a Gram-positive cocci that can cause infections but is not typically associated with sore throat.

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