ATI RN
Pediatric Immunization NCLEX Questions Ricci Questions
Question 1 of 5
A child is found to have a normal WBC count but serum concentrations of IgG, IgA, IgM, and IgE below the 95% lower limits for age. Which is the most likely diagnosis?
Correct Answer: D
Rationale: Common variable immunodeficiency (CVID) is characterized by low levels of multiple immunoglobulin classes (IgG, IgA, IgM) with normal WBC, often presenting later in childhood.
Question 2 of 5
Selective IgA deficiency is defined as serum IgA levels less than 10 mg/dL with normal levels of other immunoglobulins. The diagnosis cannot be confirmed until the patient is at least
Correct Answer: B
Rationale: IgA levels may not fully mature until after infancy, so diagnosis is typically confirmed after 4 years of age when levels should stabilize.
Question 3 of 5
A 5-month-old infant presented with reluctance to feed, lethargy, abdominal distension, and severe gingivitis. The parents are healthy relatives and give history of non-purulent omphalitis with separation of umbilical stump at the age of 2 months. His peripheral smear showed neutrophil count 24,000/mm3. Of the following, the MOST effective life saving measure is
Correct Answer: C
Rationale: Stem cell transplantation corrects leukocyte adhesion deficiency, addressing the underlying genetic defect for long-term survival.
Question 4 of 5
Which of the following best activate NAïVE CD8 lymphocytes
Correct Answer: A
Rationale: Conventional dendritic cells are the most efficient antigen-presenting cells for activating naïve CD8 T cells via cross-presentation on MHC class I.
Question 5 of 5
CD4 in secondary lymphoid organs that has not been exposed to its antigen yet is called?
Correct Answer: C
Rationale: Naïve mature T helper cells (CD4+) reside in secondary lymphoid organs before antigen exposure, distinguishing them from activated or cytotoxic cells.