ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
A CD3pos cell that secretes perforin and granzyme is a:
Correct Answer: C
Rationale: CD3+ cytotoxic T cells (CD8+) secrete perforin and granzyme to kill target cells.
Question 2 of 5
A 4.5-year-old boy presented with history of recurrent attack of secretary otitis media and purulent nasal discharge, Haemophilus influenza revealed by culture of ear discharge, on physical examination there is no tonsillar tissue and no palpable lymph nodes. Of the following, the MOST appropriate test to confirm the diagnosis is
Correct Answer: D
Rationale: The absence of lymphoid tissue and recurrent infections suggest X-linked agammaglobulinemia. Measuring antibodies to routine immunizations tests B-cell function, confirming the diagnosis.
Question 3 of 5
Which of the following statements is TRUE regarding diurnal variation of the absolute eosinophil count (AEC)?
Correct Answer: D
Rationale: Eosinophil counts are lowest in the early morning due to circadian rhythms influenced by cortisol levels, peaking later in the day.
Question 4 of 5
A 15-year-old boy with rheumatoid arthritis, on quinine for 6 months, presented with fever, aphthous stomatitis, and fatigue for the last 5 days. His absolute neutrophil count (ANC) was 700/μL. The MOST next appropriate therapeutic measure to be done when quinine withdrawal fails to improve neutropenia is
Correct Answer: D
Rationale: G-CSF stimulates neutrophil production, effectively treating drug-induced neutropenia unresponsive to withdrawal.
Question 5 of 5
The diagnosis of chronic granulomatous disease CGD is MOST often made by
Correct Answer: D
Rationale: The nitroblue tetrazolium (NBT) test assesses neutrophil oxidative burst, which is defective in CGD, making it a primary diagnostic tool.