ATI RN
Pediatrics Genetics Questions
Question 1 of 5
A cancer that spreads is termed:
Correct Answer: C
Rationale: Metastatic cancer spreads from its original site to distant tissues, unlike benign tumors.
Question 2 of 5
Which of the following is a tumor suppressor gene instead of an oncogene?
Correct Answer: C
Rationale: p53 (often written PS3 here) is a tumor suppressor; Ras, Myc, and Abl are proto-oncogenes.
Question 3 of 5
Although BRAC2 was initially found associated with breast cancer, it also increases the risk for cancers in the
Correct Answer: B
Rationale: BRCA2 (likely meant) increases risk for pancreatic cancer, among others, in addition to breast and ovarian cancer.
Question 4 of 5
Cancer cells probably arise frequently but are detected and eliminated by our immune system:
Correct Answer: A
Rationale: True. Immune surveillance eliminates many nascent cancer cells (immunoediting hypothesis).
Question 5 of 5
An extra finger in humans is rare but is due to a dominant gene. When one parent is normal and the other parent has an extra finger but is heterozygous for the trait, what is the probability that the first child will be normal?
Correct Answer: C
Rationale: Heterozygous (Aa) x normal (aa) gives 50% Aa (extra finger) and 50% aa (normal).