A boy with acute lymphoblastic leukemia is assigned to be of very high risk group if he had got which of the following features?

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Pediatric Infectious Diseases Questions

Question 1 of 5

A boy with acute lymphoblastic leukemia is assigned to be of very high risk group if he had got which of the following features?

Correct Answer: D

Rationale: t(9;22) (Philadelphia chromosome) confers a very high risk in ALL due to poor prognosis.

Question 2 of 5

During follow up of a surgically resected brain tumor, the examination of choice to distinguish recurrent tumor from radiation necrosis is

Correct Answer: B

Rationale: Magnetic resonance spectroscopy differentiates tumor recurrence from radiation necrosis by metabolic profiling.

Question 3 of 5

The LEAST likely presentation of neuroblastoma is

Correct Answer: D

Rationale: Vomiting is less specific and less common as a primary presentation of neuroblastoma compared to the others.

Question 4 of 5

A favorable prognostic factor in neuroblastoma is

Correct Answer: D

Rationale: Stage 4S neuroblastoma has a favorable prognosis with potential for spontaneous regression.

Question 5 of 5

Individuals with hereditary retinoblastoma have an increased risk for

Correct Answer: B

Rationale: Hereditary retinoblastoma (RB1 mutation) increases the risk of osteosarcoma as a second malignancy.

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