A benign tumor is one that invades locally and metastasizes to distant sites:

Questions 45

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Pediatric Genetics Questions

Question 1 of 5

A benign tumor is one that invades locally and metastasizes to distant sites:

Correct Answer: B

Rationale: False. Benign tumors do not invade or metastasize; malignant tumors do.

Question 2 of 5

Which of the following is not a familial cancer syndrome?

Correct Answer: D

Rationale: Waardenburg syndrome affects pigmentation/hearing, not cancer; others are cancer syndromes.

Question 3 of 5

A baby born with pulmonary hypoplasia secondary to oligohydramnios caused by renal agenesis would be classified as having:

Correct Answer: C

Rationale: A sequence is a cascade of anomalies from a single initiating defect (renal agenesis → oligohydramnios → pulmonary hypoplasia).

Question 4 of 5

In a Robertsonian translocation fusion occurs at the:

Correct Answer: B

Rationale: Robertsonian translocations involve fusion at centromeres of acrocentric chromosomes.

Question 5 of 5

Male to male transmission is a key feature of which pattern of inheritance?

Correct Answer: A

Rationale: Male-to-male transmission occurs in autosomal dominant inheritance; X-linked traits cannot pass from father to son.

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