A bacteriological laboratory received sputum sample of a patient suffering from tuberculosis. Bacterioscopic examination of smears and detection of tuberculosis bacillus can be realized by one of enrichment methods that involves processing of sputum only with solution of caustic soda. What is this method called?

Correct Answer: B

Rationale: The correct answer is B: Inactivation. In this method, the sputum sample is processed with a solution of caustic soda, which helps to kill any contaminants present and preserve the tuberculosis bacillus for microscopic examination. This step is crucial in ensuring accurate detection of the bacillus. A: Homogenization involves breaking down the sample to make it uniform, but it does not necessarily involve using caustic soda for inactivation. C: Flotation is a method used to separate different components based on their density and is not specific to inactivating tuberculosis bacillus. D: Filtration involves passing a sample through a filter to separate particles based on size and is not related to inactivating the tuberculosis bacillus.

Correct Answer: A

Rationale: The correct answer is A: Malaria. The patient's travel history to an endemic area like Tajikistan, along with symptoms of fever with chills, sweating, and hepatosplenomegaly, are classic for malaria. The blood test results show anemia (low RBC and hemoglobin levels), which can occur in malaria due to hemolysis. The presence of eosinophils and lymphocytes are not typical for malaria, but the overall clinical picture fits. Infectious mononucleosis (choice B) typically presents with sore throat, lymphadenopathy, and atypical lymphocytosis, which are not seen in this case. Sepsis (choice C) is characterized by systemic inflammatory response syndrome and organ dysfunction due to infection, which does not align with the symptoms and findings in the case. Typhoid fever (choice D) usually presents with gradual onset of sustained fever, abdominal pain, headache, and constipation, which are not present in this patient

Correct Answer: B

Rationale: The correct answer is B: rheumatic fever. Rheumatic fever is an inflammatory disease that can occur as a complication following a group A streptococcal infection. This is known as a post-streptococcal complication. It typically affects the heart, joints, skin, and brain. Endocarditis (choice A) is also a complication of streptococcal infections, but it is an infection of the heart valves, not an inflammatory disease like rheumatic fever. Nephritis (choice C) is inflammation of the kidneys and is not directly related to streptococcal infections. Cytomegalovirus (choice D) is a different viral infection and is not associated with streptococcal infections.

Correct Answer: B

Rationale: The correct answer is B: Proteus mirabilis. This bacterium is known to cause urinary tract infections (UTIs) and matches the description given in the question. Proteus mirabilis is a gram-negative rod-like bacterium that forms greenish mucoid colonies with a specific smell due to its production of urease enzyme. This enzyme leads to the formation of struvite crystals, which can cause painful and frequent urination. Pseudomonas aeruginosa (A) is not typically associated with UTIs. E.coli (C) is the most common cause of UTIs but does not match the specific description provided. Str.pyogenes (D) is a gram-positive bacterium and is not typically associated with UTIs.

Correct Answer: A

Rationale: The correct answer is A, Anthrax bacillus, because it has the widest infectious spectrum among the options provided. Anthrax bacillus can infect a wide range of hosts, including humans and various animals. It is known for its ability to survive in different environments and cause disease through various routes of exposure. In contrast, choices B, C, and D have more limited infectious spectra. Mumps virus primarily infects humans, the causative agent of gonorrhea mainly affects humans through sexual contact, and the rabies virus typically infects mammals through bites from infected animals. Therefore, Anthrax bacillus is the correct choice due to its broader range of hosts and modes of transmission compared to the other options.

Correct Answer: A

Rationale: The correct answer is A: Anaerobic clostridial wound infection. The symptoms and signs described (bursting pain, weakness, drowsiness, fever, swollen skin, gas crepitation, foul-smelling dark-gray discharge) are classic for gas gangrene, caused by Clostridium perfringens. Gas gangrene is an anaerobic infection that thrives in devitalized tissue, such as postoperative wounds. The gas crepitation is due to gas production by the bacteria. Abscess (B) typically presents with localized swelling and fluctuance, not gas crepitation. Postoperative wound infection (C) may present with redness, warmth, and increased wound discharge but not the specific features mentioned. Erysipelas (D) is a superficial bacterial skin infection, typically caused by Streptococcus pyogenes, presenting with well-defined raised borders and redness.

Correct Answer: A

Rationale: The correct answer is A: Amoxicillin. Amoxicillin is commonly used in combination therapy with metronidazole and bismuth compounds like De-Nol to eradicate Helicobacter pylori infection in children. Amoxicillin targets the bacterial cell wall synthesis, working synergistically with metronidazole to effectively eradicate the infection. Tetracycline (choice B) is not recommended in children under 8 years old due to potential tooth discoloration. Oleandomycin (choice C) is not commonly used for H. pylori infection. Biseptol (choice D) is a combination of sulfamethoxazole and trimethoprim, not typically used for H. pylori eradication.

Correct Answer: A

Rationale: The correct answer is A: Vibrio cholerae. This bacterium produces the cholera toxin, an enterotoxin that causes profuse watery diarrhea by disrupting the normal function of the intestines. Vibrio cholerae is specifically known for causing cholera, a severe diarrheal disease. Clostridium botulinum (B) produces botulinum toxin, causing botulism (paralysis, not diarrhea). Escherichia coli (C) can produce enterotoxins, but the question specifies a specific enterotoxin causing diarrhea, which is not a characteristic of all strains of E. coli. Streptococcus pneumoniae (D) is a common cause of respiratory infections but does not produce an enterotoxin causing diarrhea.

Correct Answer: C

Rationale: The Baltimore classification system categorizes viruses based on their genome type and replication strategy. It divides viruses into seven groups: Group I (dsDNA), Group II (ssDNA), Group III (dsRNA), Group IV (ssRNA(+)), Group V (ssRNA(-)), Group VI (ssRNA-RT), and Group VII (dsDNA-RT). Each group represents a distinct viral genome and replication method. Therefore, the correct answer is C. The other choices are incorrect because the Baltimore classification system specifically identifies viruses into seven groups, not four, five, or nine.