A 9-month-old boy presented with recurrent attacks of diarrhea, thrush, and failure to thrive shortly after birth. You suspect immune deficiency. Of the following, the MOST common cause of this condition is

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Pediatric Immunization NCLEX Questions Ricci Questions

Question 1 of 5

A 9-month-old boy presented with recurrent attacks of diarrhea, thrush, and failure to thrive shortly after birth. You suspect immune deficiency. Of the following, the MOST common cause of this condition is

Correct Answer: C

Rationale: The symptoms (diarrhea, thrush, failure to thrive) suggest severe combined immunodeficiency (SCID), most commonly due to T-cell defects, which impair both cellular and humoral immunity.

Question 2 of 5

Chronic neutropenia may be induced by

Correct Answer: C

Rationale: Cytomegalovirus can cause prolonged bone marrow suppression, leading to chronic neutropenia, unlike the others, which typically cause transient effects.

Question 3 of 5

A 15-year-old boy presented with high fever, lymphadenopathy, hepatosplenomegaly, recurrent skin infections, silvery hair, and photophobia. Last year, he developed ataxia. The MOST characteristic finding in this condition is

Correct Answer: A

Rationale: Chédiak-Higashi syndrome (silvery hair, infections, ataxia) is characterized by neutropenia due to defective neutrophil granule function.

Question 4 of 5

All the following conditions can induce lymphopenia EXCEPT

Correct Answer: D

Rationale: Cartilage-hair hypoplasia causes T-cell deficiency but not necessarily lymphopenia; the others suppress lymphocyte counts via infection or stress.

Question 5 of 5

Monoclonal antibodies (mAb) are antibodies with a wide range of clinically important applications, such as pregnancy tests, cancer diagnosis, and cancer treatment. These antibodies are and come from parent cell(s).

Correct Answer: D

Rationale: Monoclonal antibodies are identical, produced from a single parent cell (hybridoma), ensuring specificity for clinical applications.

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