ATI RN
Endocrine Pharmacology Quiz Questions
Question 1 of 5
A 76-year-old man presents to the clinic for follow-up of his benign prostatic hyperplasia. He has been doing well with his symptoms since starting finasteride. He no longer has as much difficulty starting his stream and feels that he empties his bladder completely. What is the mechanism of action of finasteride?
Correct Answer: A
Rationale: Finasteride inhibits 5alpha-reductase, reducing DHT levels, shrinking prostate size, and relieving BPH symptoms.
Question 2 of 5
A 54-year-old man with elevated cholesterol levels is treated with niacin. Within 2 weeks of starting therapy, he develops an uncomfortable feeling of warmth and itchiness. Which of the following is the most appropriate next step in the management of this patient?
Correct Answer: A
Rationale: Aspirin before niacin reduces flushing and itchiness by inhibiting prostaglandin release, a standard management strategy.
Question 3 of 5
A young married couple complains of being unable to conceive after 9 months of unprotected sex. The wife has normal TSH and FSH levels and a normal pelvic exam. They agree to a trial of letrozole to see if they can increase their fecundity. How does letrozole work?
Correct Answer: C
Rationale: Letrozole, an aromatase inhibitor, reduces estrogen production, increasing FSH and promoting ovulation to enhance fertility.
Question 4 of 5
A 57-year-old man with hyperlipidemia presents to the emergency department with severe pain in his first right toe. The pain is a 10 /10 and worse with any contact. The toe is erythematous, inflamed, and warm to touch. Joint aspiration confirms gout. He had an episode of gout about 10 years ago. What medication used to treat his hyperlipidemia may have led to his gout flare?
Correct Answer: D
Rationale: Niacin increases uric acid levels by reducing its excretion, precipitating gout flares in susceptible individuals.
Question 5 of 5
A 23-year-old healthy man receives an infusion of 100~mL of glucose solution. Which of the following curves would represent his plasma insulin concentration at 2~min after infusion?
Correct Answer: D
Rationale: Without a diagram, the insulin response curve cannot be determined; typically, insulin rises sharply within minutes of glucose infusion.