ATI RN
CNS Drugs Pharmacology Questions
Question 1 of 5
A 67-year-old man with hypertension is treated with guanethidine. He has been taking this medication for years. His blood pressure is 130/86 mm Hg. Which of the following adverse effects must this patient be aware of?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
A 43-year-old woman with a history of fibromyalgia and depression presents to her primary care physician for treatment. She complains of feeling sad and worthless in addition to multiple somatic complaints. Which of the following treatments would be best for this patient?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
A 43-year-old man who is a heroin addict is placed on methadone therapy to wean him off of heroin. Which of the following statements is true regarding the pharmacology of this agent?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following drugs acts as a competitive benzodiazepine receptor antagonist:
Correct Answer: B
Rationale: A competitive benzodiazepine receptor antagonist binds to the GABAa receptor's benzodiazepine site, preventing agonists like diazepam from exerting effects, without activating the receptor itself. Flumazenil is this antagonist, used to reverse benzodiazepine overdose (e.g., reversing sedation or respiratory depression) by competitively displacing agonists. Naloxone (choice A) is an opioid antagonist, targeting mu receptors to reverse opioid overdose, not benzodiazepine-related. Flurazepam (choice C) is a benzodiazepine agonist, promoting GABA effects, not blocking them. Disulfuram (choice D, likely misspelled) inhibits aldehyde dehydrogenase for alcoholism treatment, unrelated to benzodiazepine receptors. Flumazenil's specificity and competitive nature make it the correct choice. This question emphasizes antidote recognition, critical in emergency settings to counteract CNS depression, distinguishing it from other reversal agents like Naloxone.
Question 5 of 5
Aspirin is used in treatment of:
Correct Answer: D
Rationale: Aspirin (acetylsalicylic acid) is used in acute rheumatic fever (choice D) for its anti-inflammatory and analgesic effects, reducing joint pain and inflammation in this autoimmune condition post-streptococcal infection. Vertigo (choice A) isn't an inflammatory condition aspirin targets. Peptic ulcer (choice B) is a contraindication, as aspirin exacerbates ulceration via COX-1 inhibition. Acute bronchial asthma (choice C) may worsen with aspirin due to leukotriene overproduction in sensitive patients. Acute rheumatic fever aligns with aspirin's anti-inflammatory utility, making it the correct therapeutic indication.