ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
A 66-year-old man with advanced pancreatic cancer develops cachexia (loss of mass) Which cytokine is primarily responsible for the cachexia seen in certain patients with cancer or debilitating infections?
Correct Answer: D
Rationale: TNF-α drives cachexia by promoting muscle wasting and metabolic changes in cancer.
Question 2 of 5
Which of the following peripheral immune tissues is likely to be different from teen through life to old age?
Correct Answer: C
Rationale: The thymus involutes with age, reducing T cell output.
Question 3 of 5
A 4.5-year-old boy presented with history of recurrent attack of secretary otitis media and purulent nasal discharge, Haemophilus influenza revealed by culture of ear discharge, on physical examination there is no tonsillar tissue and no palpable lymph nodes. Of the following, the MOST appropriate test to confirm the diagnosis is
Correct Answer: D
Rationale: The absence of lymphoid tissue and recurrent infections suggest X-linked agammaglobulinemia. Measuring antibodies to routine immunizations tests B-cell function, confirming the diagnosis.
Question 4 of 5
Which of the following statements is TRUE regarding diurnal variation of the absolute eosinophil count (AEC)?
Correct Answer: D
Rationale: Eosinophil counts are lowest in the early morning due to circadian rhythms influenced by cortisol levels, peaking later in the day.
Question 5 of 5
A 15-year-old boy with rheumatoid arthritis, on quinine for 6 months, presented with fever, aphthous stomatitis, and fatigue for the last 5 days. His absolute neutrophil count (ANC) was 700/μL. The MOST next appropriate therapeutic measure to be done when quinine withdrawal fails to improve neutropenia is
Correct Answer: D
Rationale: G-CSF stimulates neutrophil production, effectively treating drug-induced neutropenia unresponsive to withdrawal.