A 64-year-old man suffering from benign prostatic hyperplasia presented to his physician complaining of generalized itching. The problem began 1 week earlier, after an afternoon of prolonged sun exposure. The patient reported that the itching was distressing, especially during the night. Physical examination showed an enlarged prostate and no other evidence of ongoing disease. Which of the following drugs would be appropriate for this patient?

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ATI Pharmacology Across the Lifespan Questions

Question 1 of 5

A 64-year-old man suffering from benign prostatic hyperplasia presented to his physician complaining of generalized itching. The problem began 1 week earlier, after an afternoon of prolonged sun exposure. The patient reported that the itching was distressing, especially during the night. Physical examination showed an enlarged prostate and no other evidence of ongoing disease. Which of the following drugs would be appropriate for this patient?

Correct Answer: D

Rationale: The correct answer is D: Loratadine. Loratadine is a second-generation antihistamine that is commonly used to relieve symptoms of allergies, including itching. In this case, the patient's generalized itching is likely due to an allergic reaction triggered by sun exposure. Loratadine can help alleviate the itching without causing excessive sedation, making it suitable for an elderly patient. A: Cyproheptadine is a first-generation antihistamine that can cause significant sedation and anticholinergic side effects, making it less ideal for an elderly patient. B: Diphenhydramine is also a first-generation antihistamine that can cause sedation and anticholinergic side effects, which may not be well-tolerated by the elderly patient. C: Famotidine is a histamine-2 (H2) receptor antagonist used to reduce stomach acid production and treat ulcers, not itching related to allergic reactions.

Question 2 of 5

A28-year-old woman who was 26 weeks' pregnant had been recently diagnosed with classic migraine. Which of the following drugs would be appropriate to reduce the frequency and severity of her migraine attacks?

Correct Answer: B

Rationale: The correct answer is B: Propranolol. Propranolol is a beta-blocker commonly used to prevent migraines by reducing the frequency and severity of attacks. It works by blocking the action of certain natural chemicals in the body that trigger migraines. Choice A, Ergonovine, is not indicated for migraine prevention and is used for other purposes. Choice C, Ergotamine, is an older medication with more side effects and contraindications compared to propranolol. Choice D, Valproic acid, is also used for migraine prevention but may not be the best choice for a pregnant woman due to potential risks to the fetus.

Question 3 of 5

What does 'pharmacokinetics' include?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Pick out the parenteral route of medicinal agent administration:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Tick the drug type for which microsomal oxidation is the most prominent:

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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