A 64-year-old alcoholic man who has not had access to alcohol for days is brought to the hospital by family. He is extremely agitated and reports seeing spiders on the walls that he wants to kill. His temperature is 39°C, pulse is 96 beats/minute, and blood pressure is 152/88 mm Hg. He is given a benzodiazepine, which mimics the effects of alcohol on his brain. Which of the following types of receptor to benzodiazepines is acted upon?

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Pharmacology ATI Quizlet Questions

Question 1 of 5

A 64-year-old alcoholic man who has not had access to alcohol for days is brought to the hospital by family. He is extremely agitated and reports seeing spiders on the walls that he wants to kill. His temperature is 39°C, pulse is 96 beats/minute, and blood pressure is 152/88 mm Hg. He is given a benzodiazepine, which mimics the effects of alcohol on his brain. Which of the following types of receptor to benzodiazepines is acted upon?

Correct Answer: D

Rationale: Alcohol withdrawal (hallucinations, agitation) is treated with benzodiazepines, acting on GABA-A ion channels . They enhance chloride influx, mimicking alcohol's calming effect. Options , , are fictional. Transcription factor (E) is unrelated. This mechanism stabilizes his withdrawal symptoms.

Question 2 of 5

The student nurse asks the nursing instructor why he needs to take anatomy and physiology, as well as microbiology, when he only wants to learn about pharmacology. What is the best response by the instructor?

Correct Answer: C

Rationale: Anatomy, physiology, and microbiology underpin pharmacology, enabling nurses to grasp drug actions and patient responses, enhancing care through informed medication use. As an outgrowth oversimplifies their integration. Curriculum mandates explain requirements, not value. Understanding is key, but applying it to care-like knowing antibiotic targets or drug effects on organs-grounds pharmacology in practice, making it the best rationale.

Question 3 of 5

Which statement is false:

Correct Answer: C

Rationale: Higher potency (lower dose for effect) can coexist with lower efficacy (max effect), true, as potency reflects affinity, not ceiling effect. Higher receptor affinity increases potency, true, per receptor theory. Lower potency doesn't mandate lower efficacy; a less potent drug can achieve the same max effect with more dose, making this false. Higher potency with equal efficacy is true (e.g., partial agonists). This pharmacodynamic distinction is vital for drug selection, where efficacy often trumps potency.

Question 4 of 5

The home health nurse notes that the elderly patient doubled up on his pain medication, even though the prescribed dose was at a therapeutic level. The patient says, 'If one pill is good, two pills are better.' Which statement best describes the result of the patient's action?

Correct Answer: D

Rationale: Doubling a therapeutic dose exceeds the plateau-efficacy maxes out, but side effects (e.g., sedation) rise with excess, especially in the elderly with slower clearance. Tolerance needs chronic use, not one event. More relief assumes linear gain, not true. Tolerance requiring more is future, not immediate. Side effects reflect pharmacodynamics, a key risk.

Question 5 of 5

Which of the following is suitable for immediate treatment of an 18-year-old woman presenting with weight loss, tachycardia and a goitre?

Correct Answer: D

Rationale: Weight loss, tachycardia, and goitre suggest hyperthyroidism (e.g., Graves'). Verapamil controls rate but not thyroid function. Radioactive iodine (131I) treats long-term, not immediately. Carbamazepine is for seizures, L-thyroxine worsens hyperthyroidism. Atenolol, a beta-blocker, immediately reduces tachycardia and symptoms by blocking adrenergic effects, suitable for acute management while awaiting antithyroid drugs (e.g., propylthiouracil). Its symptomatic relief is critical in hyperthyroid crises.

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