A 63-year-old woman presents with a productive cough, shortness of breath, and fever and chills. Past medical history is significant for chronic renal disease. After a standard dose of which of the following drugs would you expect to see the greatest increase in serum drug concentration?

A 63-year-old woman presents with a productive cough, shortness of breath, and fever and chills. Past medical history is significant for chronic renal disease. After a standard dose of which of the following drugs would you expect to see the greatest increase in serum drug concentration?

A 24-year-old primigravid woman’s water breaks at 39 weeks gestation. Twenty-four hours later, she is having regular contractions 3 min apart. Her labor lasts 8 h. At the hospital, she gives birth to a baby boy, who initially appeared healthy. Within the next 12 h, the baby boy begins to have temperature fluctuations, difficulty breathing, and reduced movements. You suspect neonatal sepsis, so IV ampicillin is started. Which additional antibiotic could be given simultaneously to have a synergistic effect in controlling this infection?

A 19-year-old college student man presents to the student health service with a 2-week history of headache, malaise, sore throat, and dry cough, which has become productive over the last 4 days. He states that several of his dorm mates have complained of similar problems in the last few weeks. Pulmonary auscultation reveals scattered coarse rhonchi bilaterally. What is the best treatment for this patient?

A 12-year-old male complains of red plaques covered by silver scales on his elbows and knees. He has one older sister with similar lesions. In each case, the lesions are worse in the winter months. His pediatrician prescribes acitretin. Which of the following may this boy experience as a result of this treatment?

An 18-year-old male college student presents to the emergency room with a fever of 103°F and stiff neck for the past 3 h. After a lumbar puncture and Gram stain, the diagnosis of meningococcal meningitis is established. Unfortunately, his college did not require students to have the meningococcal vaccine. What prophylaxis should be given to his close contacts in the dorm?