A 60-year-old woman suffers an anterior wall myocardial infarction. She recovers well initially but soon develops left heart failure. Her physician prescribes multiple medications to treat different aspects of heart failure, including isosorbide dinitrate. What is the mechanism of action of this agent?

A 60-year-old woman suffers an anterior wall myocardial infarction. She recovers well initially but soon develops left heart failure. Her physician prescribes multiple medications to treat different aspects of heart failure, including isosorbide dinitrate. What is the mechanism of action of this agent?

A 52-year-old woman presents to the primary care clinic with progressive weakness and muscle aches for the past month. She can still do her daily tasks but can notice a difference in her strength. When she lies down at night, her legs always ache. Her electrolytes are significant for a K⁺ of 2.9 mEq/L. She was recently started on a diuretic for peripheral edema. She is pleased that she has not had peripheral edema since starting the diuretic. What is the most appropriate diuretic to treat this patient?

The following adverse effects are associated with amiodarone:

A patient who has been taking an oral antihypertensive drug for about a year develops a positive Coombs' test. Which of the following drugs is the most likely cause?