Questions 9

ATI RN

ATI RN Test Bank

Mastering Microbiology Test Bank Questions

Question 1 of 5

A 6-year-old child has duodenal ulcer. What antibacterial drug should be co-administered together with metronidazole and De-Nol in order to eradicate Helicobacter pylori infection?

Correct Answer: A

Rationale: The correct answer is A: Amoxicillin. Amoxicillin is commonly used in combination therapy with metronidazole and bismuth compounds like De-Nol to eradicate Helicobacter pylori infection in children. Amoxicillin targets the bacterial cell wall synthesis, working synergistically with metronidazole to effectively eradicate the infection. Tetracycline (choice B) is not recommended in children under 8 years old due to potential tooth discoloration. Oleandomycin (choice C) is not commonly used for H. pylori infection. Biseptol (choice D) is a combination of sulfamethoxazole and trimethoprim, not typically used for H. pylori eradication.

Question 2 of 5

A patient of surgical department complains about pain in the small of her back and in the lower part of her belly; painful and frequent urination. Bacteriological examination of urine revealed gram-negative oxidase-positive rod-like bacteria forming greenish mucoid colonies with specific smell. What causative agent can it be?

Correct Answer: B

Rationale: The correct answer is B: Proteus mirabilis. This bacterium is known to cause urinary tract infections (UTIs) and matches the description given in the question. Proteus mirabilis is a gram-negative rod-like bacterium that forms greenish mucoid colonies with a specific smell due to its production of urease enzyme. This enzyme leads to the formation of struvite crystals, which can cause painful and frequent urination. Pseudomonas aeruginosa (A) is not typically associated with UTIs. E.coli (C) is the most common cause of UTIs but does not match the specific description provided. Str.pyogenes (D) is a gram-positive bacterium and is not typically associated with UTIs.

Question 3 of 5

Which of the following is a folate antagonist?

Correct Answer: B

Rationale: The correct answer is B: Trimethoprim. Trimethoprim is a folate antagonist that inhibits dihydrofolate reductase, an enzyme essential for folate metabolism in bacteria. This disrupts bacterial DNA synthesis, leading to bacteriostatic effects. Methyl Penicillin (A) is a beta-lactam antibiotic that interferes with bacterial cell wall synthesis. Vancomycin (C) inhibits cell wall synthesis by binding to D-Ala-D-Ala terminus of cell wall precursors. Gentamicin (D) inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome.

Question 4 of 5

Bacteria causing bacillary dysentery can be isolated from the patient's blood:

Correct Answer: A

Rationale: Rationale: 1. Bacillary dysentery primarily affects the intestinal tract, not the bloodstream. 2. Bacteremia is rare in bacillary dysentery, as the infection is localized. 3. Isolating bacteria from the blood is not a typical diagnostic feature. 4. Therefore, the correct answer is A. Summary: Bacteria causing bacillary dysentery are not typically isolated from the patient's blood due to the localized nature of the infection. Choices B and C are incorrect as they suggest specific timeframes, which are not relevant to bacteremia in this context. Choice D is incorrect as bacteremia is not associated with bacillary dysentery.

Question 5 of 5

What is the primary mode of transmission for tetanus?

Correct Answer: C

Rationale: The correct answer is C: Contaminated wounds. Tetanus is caused by the bacterium Clostridium tetani, which enters the body through breaks in the skin such as wounds or cuts. The bacteria produce a toxin that affects the nervous system, leading to muscle stiffness and spasms. Ingestion of contaminated food (choice A) is not a mode of transmission for tetanus. Inhalation of droplets (choice B) is more relevant for respiratory infections. Direct physical contact (choice D) is not the primary mode of transmission for tetanus as the bacteria need a portal of entry such as a wound to cause infection.

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