A 6-year-old boy is brought to his primary care physician with a history of hay fever and asthma. He usually has two to three attacks per week. For symptom control, he uses an albuterol inhaler, but his parents would like to try something more. They would like him to take something that would lessen the amount of attacks he has. Although corticosteroids would probably work best for prophylaxis, they are contraindicated in children. He is instead given montelukast. How does montelukast work?

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Practice ATI B Exam Pharmacology Questions

Question 1 of 5

A 6-year-old boy is brought to his primary care physician with a history of hay fever and asthma. He usually has two to three attacks per week. For symptom control, he uses an albuterol inhaler, but his parents would like to try something more. They would like him to take something that would lessen the amount of attacks he has. Although corticosteroids would probably work best for prophylaxis, they are contraindicated in children. He is instead given montelukast. How does montelukast work?

Correct Answer: A

Rationale: Montelukast prevents asthma attacks by blocking leukotriene receptors . Leukotrienes drive inflammation; montelukast reduces this, complementing albuterol's acute relief. Muscarinic blockade is ipratropium's action. COX inhibition (C, D) is NSAIDs'. Lipoxygenase inhibition (E) is zileuton's. Montelukast's specificity suits prophylaxis in this child.

Question 2 of 5

Discharge planning for the client prescribed tetracycline will include which instruction?

Correct Answer: C

Rationale: Tetracycline is a broad-spectrum antibiotic that can be rendered ineffective if taken with certain substances that interfere with its absorption. Dairy products, such as milk, contain calcium, which binds to tetracycline in the gastrointestinal tract, forming insoluble complexes that prevent the drug from being absorbed into the bloodstream. This interaction significantly reduces its therapeutic efficacy, making it crucial to instruct the client to avoid milk when taking the medication. Similarly, antacids (containing magnesium, aluminum, or calcium) and iron supplements also chelate tetracycline, decreasing its bioavailability, so choices A and B are incorrect and potentially harmful instructions. Reducing vitamin intake is unrelated to tetracycline's administration or efficacy, as vitamins do not typically interfere with its action unless specifically combined with minerals like iron or calcium. Therefore, the priority instruction is to avoid milk, ensuring the drug's effectiveness, which makes choice C the correct and most critical discharge teaching point.

Question 3 of 5

A patient says, 'I have such bad seasonal allergies. Is there anything I can take to keep them from happening?' What information should the nurse provide?

Correct Answer: C

Rationale: Preventing seasonal allergies involves blocking histamine (antihistamines, choice A), reducing inflammation (corticosteroids, choice B), or stabilizing mast cells . Mast cell stabilizers (e.g., cromolyn) prevent histamine release, a proactive approach. Decongestants relieve symptoms, not prevent. Choice C highlights a preventive mechanism, key for allergy management education.

Question 4 of 5

A patient who reports severe seasonal allergies has been prescribed fluticasone (Flonase). The nurse providing medication information would collaborate with the prescriber if the patient makes which statement?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

The nurse is caring for a client receiving gentamicin (Garamycin). Which instruction should the nurse include?

Correct Answer: A

Rationale: Gentamicin risks ototoxicity, causing tinnitus (ringing, choice A), a serious sign needing immediate reporting to prevent hearing loss. Food doesn't apply'IV delivery. Calcium is irrelevant. Stopping early risks resistance. Reporting tinnitus aligns with gentamicin's toxicity profile, critical in therapy where auditory damage is irreversible, making A the key instruction.

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