ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
A 59-year-old man with Parkinson's disease begins a course of bromocriptine in hopes of improving his significant symptoms of cogwheel rigidity and bradykinesia. After being on the medication for 6 months, a renal ultrasound is obtained that reveals bilateral hydronephrosis and elevation of his serum creatinine to 2.5 mg/dL. What is the most likely explanation for these findings?
Correct Answer: C
Rationale: Bromocriptine, a dopamine agonist, can cause retroperitoneal fibrosis, leading to ureteral obstruction and hydronephrosis.
Question 2 of 5
A 72-year-old man is brought to his physician by his son. The son complains that this patient has been becoming forgetful, confused, moody, and aggressive over the past few months. One drug that may be used to treat this patient's symptoms is donepezil. Which of the following describes an effect of donepezil?
Correct Answer: D
Rationale: Donepezil, a cholinesterase inhibitor, increases synaptic acetylcholine levels by preventing its breakdown, improving cognitive function in Alzheimer's disease.
Question 3 of 5
Acute or chronic colchicine toxicity may be identified by which signs/symptoms?
Correct Answer: D
Rationale: Colchicine toxicity can lead to alopecia, bone marrow suppression (blood dyscrasias), and severe gastrointestinal effects such as diarrhea and vomiting.
Question 4 of 5
A 7-year-old boy is brought to the emergency department by his parents after being stung by a bee. The parents say that he is allergic to bee stings, and the patient is having great difficulty breathing. Epinephrine is administered immediately. His symptoms improve as molecules of epinephrine bind to β\(_2\)-receptors in bronchial smooth muscle. Which of the following describes a feature of β\(_2\)-receptors?
Correct Answer: A
Rationale: β\(_2\)-adrenergic receptors are G-protein-coupled receptors that have seven transmembrane domains, which is a characteristic feature of this receptor family.
Question 5 of 5
Choose the correct statement from the following
Correct Answer: C
Rationale: Picrotoxin is a GABA-A receptor antagonist that blocks chloride channels, leading to convulsant effects.