ATI RN
Endocrine Pharmacology Quizlet Questions
Question 1 of 5
A 57-year-old man with Type-2 diabetes presents to the primary care clinic for follow-up. He has been taking metformin and has had good control of his sugars. He denies any hypoglycemic episodes or peripheral neuropathy. His hemoglobin \A_{1c is 8.3%, which is increased from 7.9% previously. The physician decides to add miglitol to his regimen. What is the mechanism of action of miglitol?
Correct Answer: D
Rationale: Miglitol, an alpha-glucosidase inhibitor, slows carbohydrate absorption by inhibiting intestinal brush border enzymes, reducing postprandial glucose.
Question 2 of 5
Regarding the biosynthesis of thyroid hormones, if a novel medication was developed to block the proteolytic release of hormones, this medication would act at which of the following sites?
Correct Answer: D
Rationale: Without a diagram, assuming standard thyroid hormone synthesis steps, proteolytic release of T3/T4 from thyroglobulin occurs late (e.g., Location 4), which this drug would target.
Question 3 of 5
A 55-year-old man presents to his primary care physician to follow up on his hyperlipidemia medication. Lab work suggests that his total cholesterol, LDL, triglycerides, and HDL are all within normal limits because of the lovastatin he began taking 2 months ago. He has not visited the office since being prescribed this medication. Which of the following lab tests should be obtained at the present office visit?
Correct Answer: C
Rationale: Lovastatin requires liver function tests (LFTs) after initiation to monitor for hepatotoxicity, a standard follow-up step.
Question 4 of 5
A patient presents with lethargy, tiredness, cold intolerance, dryness of skin and hair, hoarsness of voice and weight gain. He also has psychosis and his heart rate appears to be lower than normal. Which of the following is not associated with the presenting symptoms?
Correct Answer: D
Rationale: Hypothyroidism symptoms (lethargy, weight gain, etc.) are linked to Hashimoto's, cretinism, and iodine deficiency (low thyroid hormone). Increased iodine levels would cause hyperthyroidism, not these symptoms.
Question 5 of 5
A patient presents with tiredness, weakness, anorexia, apathy, abdominal pain, hyperpigmentation and postural hypertension. Upon infection he appears to be in cardiogenic shock and his blood volume is depleted. His sodium levels are low, potassium levels are high. Which of the following would also be elevated?
Correct Answer: D
Rationale: Addison's disease (adrenal insufficiency) causes hyperpigmentation, hyponatremia, hyperkalemia, and shock due to low cortisol; ACTH is elevated due to lack of negative feedback.