ATI RN
Endocrine Pharmacology Quiz Questions
Question 1 of 5
A 56-year-old woman with diabetes who takes metformin is scheduled to undergo a CT scan of the abdomen and pelvis with IV contrast. Her last dose of metformin was this morning. She presents to the imaging center ready for the test. When she tells the technician that she takes metformin, her CT scan is cancelled despite her serum creatinine being 1mg\dL. What is the reason for cancellation of the test?
Correct Answer: B
Rationale: Metformin is held before contrast due to the risk of lactic acidosis if contrast-induced nephropathy impairs metformin clearance, even with normal creatinine.
Question 2 of 5
A 67-year-old man injures his shoulder in an ATV accident. Over-the-counter and prescription ibuprofen are unable to control the pain and swelling satisfactorily. The patient asks about glucocorticoid injections, so his doctor begins to explain the myriad effects of glucocorticoids in the body. How might glucocorticoids help this patient?
Correct Answer: B
Rationale: Glucocorticoids inhibit phospholipase \A_2, reducing prostaglandin and leukotriene synthesis, thus decreasing inflammation and pain in the shoulder.
Question 3 of 5
A 43-year-old man with dyslipidemia comes to the clinic for a routine checkup. He currently takes atorvastatin but is not achieving his target lipid profile. The physician prescribes colesevelam to help. Which of the following changes is expected as a result of this new therapy?
Correct Answer: C
Rationale: Colesevelam, a bile acid sequestrant, can cause hyperglycemia by reducing insulin sensitivity, though it lowers LDL.
Question 4 of 5
A week-old newborn male presents to clinic for a routine checkup. His birth history and delivery were uncomplicated. He is being breastfed and has had no difficulty feeding. The parents are concerned because he does not seem to have male genital characteristics. Physical examination reveals female external genitalia seen without a scrotum or descended testicles. What androgen is the patient lacking that is the cause of his condition?
Correct Answer: D
Rationale: DHT is critical for male external genitalia development; its absence (e.g., in 5alpha-reductase deficiency) results in female-appearing genitalia despite XY karyotype.
Question 5 of 5
An 18-year-old female with diabetes presents to the clinic for her annual visit. Over the past year, she has experienced daily nausea and occasional vomiting. She has learned that eating small amounts of food at a time helps to decrease the frequency of vomiting. She is diagnosed with diabetic gastroparesis and started on metoclopramide. What is a side effect of metoclopramide?
Correct Answer: D
Rationale: Metoclopramide, a prokinetic, can cause tardive dyskinesia, a serious movement disorder, with prolonged use.