A 55-year-old man with a 40 pack-year history of smoking develops agranulocytosis and some leukemic features. His physical examination of the heart, lungs, and abdomen are within normal limits. Should this disease relate to a potential toxic exposure, which of the following should be considered most likely?

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ATI Pharmacology Exam Practice Questions

Question 1 of 5

A 55-year-old man with a 40 pack-year history of smoking develops agranulocytosis and some leukemic features. His physical examination of the heart, lungs, and abdomen are within normal limits. Should this disease relate to a potential toxic exposure, which of the following should be considered most likely?

Correct Answer: A

Rationale: Agranulocytosis and leukemic features in a smoker suggest benzene exposure. Benzene, in tobacco smoke, causes bone marrow toxicity. Ethylene alcohol , carbon tetrachloride , methanol , and toluene (E) don't link to leukemia. Benzene's carcinogenicity fits this profile.

Question 2 of 5

Patients should avoid what drink while taking Alprazolam?

Correct Answer: B

Rationale: Patients taking Alprazolam should avoid consuming grapefruit juice. Grapefruit juice can interfere with the metabolism of Alprazolam in the body, leading to increased levels of the medication in the bloodstream. This can potentiate the sedative effects of Alprazolam and increase the risk of side effects or overdose. It is best to consult with a healthcare provider or pharmacist regarding any potential interactions with grapefruit juice and medications.

Question 3 of 5

Drugs can cause adverse events in a patient. Bone marrow toxicity is one of the most frequent types of drug-induced toxicity. The most serious form of bone marrow toxicity is:

Correct Answer: A

Rationale: Aplastic anemia is the most severe form of bone marrow toxicity, characterized by pancytopenia and bone marrow failure. It can be life-threatening and requires immediate intervention. Thrombocytosis, leukocytosis, and granulocytosis are not typically associated with drug-induced bone marrow toxicity.

Question 4 of 5

A patient was admitted to the emergency department with a pulse oximeter reading of 85% after a successful prehospital resuscitation from cardiac arrest due to an asthma attack. What is the most important initial drug to administer as ordered?

Correct Answer: D

Rationale: Oxygen is the most important initial intervention for a patient with a low pulse oximeter reading (85%) to correct hypoxia and prevent further complications. While epinephrine (A) and albuterol (C) are used to treat asthma, oxygen is the priority to address the immediate hypoxia. Sodium bicarbonate (B) is not indicated unless there is severe metabolic acidosis.

Question 5 of 5

The adolescent is supposed to go to the school nurse at 12:00 to receive his medication for attention-deficit hyperactivity disorder (ADHD). He often does not go for the medication. What best describes the nurse's understanding of this situation?

Correct Answer: A

Rationale: Adolescents prioritize peer image-skipping ADHD meds (e.g., Ritalin) at school likely stems from embarrassment, a developmental trait. Lack of understanding or forgetting is possible but less likely with routine. Conscious refusal needs evidence (e.g., verbal rejection). Embarrassment fits social sensitivity, guiding intervention.

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