ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
A 55-year-old executive has cardiomyopathy and congestive heart failure. He is being treated with diuretics. The mechanism of action of furosemide is best described as
Correct Answer: B
Rationale: Furosemide blocks the Na+/K+/2Cl cotransporter in the thick ascending limb of the loop of Henle, increasing urine output.
Question 2 of 5
Which one of the following anticancer drugs acts in the M-phase of the cell cycle to prevent disassembly of the mitotic spindle?
Correct Answer: C
Rationale: Paclitaxel stabilizes microtubules, preventing their disassembly during the M-phase, arresting cell division.
Question 3 of 5
In antiviral immunity, what directly recognized and kills viral-infected cells?
Correct Answer: A
Rationale: Cytotoxic T cells (CTLs) directly recognize and kill virus-infected cells via MHC class I presentation.
Question 4 of 5
Which is a valid comparison of live, attenuated and killed, inactivated active vaccines?
Correct Answer: A
Rationale: Live attenuated vaccines replicate, boosting immunity with lower doses, unlike killed vaccines which often require boosters.
Question 5 of 5
Gamma immunoglobulin is considered
Correct Answer: C
Rationale: Gamma immunoglobulin (IgG) is a protein, specifically an antibody, produced by B cells.